Gene rearrangements in T‐cell lymphoblastic lymphoma
Gene rearrangements in T‐cell lymphoblastic lymphoma
复制标题
T细胞淋巴母细胞淋巴瘤的基因重排
作者：
E. Pilozzi;H. Müller;B. Falini;Chris De Wolf‐Peeters;C. Fidler;K. Gatter;J. Wainscoat
本研究对一系列39例CD 3阳性T细胞急性淋巴细胞白血病（ALL）伴和不伴CD 79 a共表达的病例进行了IG重链（IgH）和T细胞受体γ（TCRγ）基因检查; 30/39例病例存在TCRγ基因重排，其中2例也显示IgH重排。无一例仅发生IgH重排。该研究的结论是，CD 3阳性的淋巴母细胞淋巴瘤病例属于T细胞谱系，无论CD 79 a表达如何。版权所有© 1999约翰威利父子有限公司.
This study presents an examination of the Ig heavy chain (IgH) and T‐cell receptor gamma (TCRγ) genes in a series of 39 CD3‐positive T‐cell acute lymphoblastic leukaemia (ALL) cases with and without co‐expression of CD79a; 30/39 cases had a rearrangement of the TCRγ genes and two of these 30 cases also demonstrated an IgH rearrangement. No cases had solely an IgH rearrangement. The conclusion of the study is that lymphoblastic lymphoma cases that are positive for CD3 are of T‐cell lineage, regardless of CD79a expression. Copyright © 1999 John Wiley & Sons, Ltd.
T细胞和非T、非B急性淋巴细胞白血病的基因型和表型。
影响因子：
20.3
作者：
Aisenberg,AC;Wilkes,BM
通讯作者：
Wilkes,BM
T细胞急性淋巴细胞白血病中免疫球蛋白重链基因的重排。
影响因子：
20.3
作者：
Kitchingman,GR;Rovigatti,U;Mauer,AM;Melvin,S;Murphy,SB;Stass,S
通讯作者：
Stass,S