Synthesis of multiply functionalized benzenes via ruthenium-catalyzed cycloaddition of diiododiynes
Synthesis of multiply functionalized benzenes via ruthenium-catalyzed cycloaddition of diiododiynes
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DOI：
10.1016/j.tet.2007.09.086
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发表时间：
2008-01-28
期刊：
影响因子：
2.1
通讯作者：
Hattori, Kozo
中科院分区：
文献类型：
--
作者：
Yamamoto, Yoshihiko;Hattori, Kozo
通过钯催化的二碘二炔与乙炔基硼酸酯或末端炔的[2+2+2]环加成反应，以及随后的化学选择性和区域选择性钯催化的C-C键形成反应，精确地合成了高度官能化的苯。采用顺序环加成/偶联法合成了低聚对苯乙炔。(c)2007爱思唯尔有限公司保留所有权利。
Highly functionalized benzenes were precisely synthesized via multi-step processes consisting of ruthenium-catalyzed [2+2+2] cycloaddition of diiododiynes with an ethynylboronate or terminal alkynes, and subsequent chemo- and regio-selective palladium-catalyzed C-C bond-forming reactions of the resulting cycloadducts. The sequential cycloaddition/coupling process was applied to the synthesis of oligo(p-phenylene ethynylene)s. (c) 2007 Elsevier Ltd. All rights reserved.