Neurochemistry and electroanalytical probes.

Neurochemistry and electroanalytical probes.
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DOI:
10.1016/s1367-5931(02)00374-5
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发表时间:
2002-10
影响因子:
7.8
通讯作者:
Kevin P. Troyer;M. Heien;B. J. Venton;R. Wightman
Kevin P. Troyer;M. Heien;B. J. Venton;R. Wightman
中科院分区:
生物学2区
文献类型:
--
作者:
Kevin P. Troyer;M. Heien;B. J. Venton;R. Wightman

文献摘要

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电分析技术已被应用于监测化学事件,包括啮齿动物行为过程中神经递质的释放和单细胞释放分子的齐托摩尔。已经建立了转基因小鼠模型并进行了研究,以在体外鉴定特定的细胞类型。电分析探针的表征和表面修饰提高了测量的选择性和灵敏度。
Electroanalytical techniques have been applied to monitoring chemical events including neurotransmitter release during rodent behaviour and the release of zeptomoles of molecules from single cells. Transgenic mice models have been developed and studied to identify specific cell types in vitro. Characterization and surface modification of electroanalytical probes has enhanced the selectivity and sensitivity of measurements.