Exposure to uncontrollable stress and the postimperative negative variation (PINV): Prior control matters
Exposure to uncontrollable stress and the postimperative negative variation (PINV): Prior control matters
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DOI：
10.1016/j.biopsycho.2008.09.002
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发表时间：
2009-02-01
影响因子：
2.6
通讯作者：
Flor, Herta
中科院分区：
文献类型：
--
作者：
Diener, Carsten;Struve, Maren;Flor, Herta
本研究的主要目标是评估由不可控制的压力引起的命令后负变异（PINV）所指示的皮质功能。六十六人被随机分配到三组，接受不同顺序的压力源控制。在 S1-S2 范式中，一组最初对厌恶刺激有控制，随后失去控制并恢复控制。其他组最初经历的是不可控或可控，然后是控制状态。不受控制的应力显着增强了 PINV 幅度，与之前的控制无关。然而，在失去控制之前对厌恶刺激的控制使 PINV 在恢复控制期间正常化。之前没有经历过控制的人在控制恢复期间表现出增强的 PINV、更长的反应时间和更多错误。我们的结论是，皮质激活的变化与工具性突发事件的评估有关。然而，参与处理无法控制的压力的大脑区域的确切确定需要进一步研究。 (C) 2008 Elsevier B.V. 保留所有权利。
The main goal of this study was to assess cortical functioning as indexed by the postimperative negative variation (PINV) induced by uncontrollable stress. Sixty-six persons were randomly assigned to three groups who underwent different sequences of stressor controllability. Within an S1-S2 paradigm, one group had initial control over aversive stimulation followed by loss of control and restitution of control. The other groups initially experienced either uncontrollability or controllability followed by a condition of control. Uncontrollable stress significantly enhanced PINV magnitudes independent of preceding control. However, control over aversive stimulation prior to loss of control normalized PINVs during restitution of control. Persons not experiencing prior control showed enhanced PINVs, longer reaction times, and more errors during restitution of control. We conclude that cortical activation changes are linked to the evaluation of instrumental contingencies. However, the exact determination of brain regions involved in the processing of uncontrollable stress needs further investigation. (C) 2008 Elsevier B.V. All rights reserved.