Predictors of fear of recurrence in patients one year after cancer rehabilitation: A prospective study

Predictors of fear of recurrence in patients one year after cancer rehabilitation: A prospective study
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DOI:
10.3109/0284186x.2013.765063
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发表时间:
2013-08-01
期刊:
影响因子:
3.1
通讯作者:
Dinkel, Andreas
Dinkel, Andreas
中科院分区:
医学3区
文献类型:
--
作者:
Mehnert, Anja;Koch, Uwe;Dinkel, Andreas

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背景对癌症复发(FCR)或癌症进展的恐惧是癌症患者最常见的痛苦心理症状之一。与ICD-10或DSM-IV中的焦虑症不同,FCR描述的是对危及生命的疾病的真实的威胁的情绪反应。FCR水平升高可能会导致功能失调,导致社会功能的严重破坏,并影响健康和生活质量(QoL)。我们检查了癌症患者在康复计划期间和之后FCR的患病率和病程,并调查了人口统计学、医学和心理社会因素之间的关联。我们进一步旨在确定癌症康复后一年FCR的预测因素。方法.在诊断后平均11个月连续招募了共计N = 1281例合格患者(77.5%的参与率),并在开始(t(1))(1148)、结束(t(2))(1060)和康复后12个月(t(3))(n = 883)进行了评估。参与者完成了评估FCR,焦虑,抑郁,QoL,社会支持以及一系列癌症和治疗相关特征的有效措施。结果在t(1),我们的样本中有18.1%被归类为具有高水平的FCR,66.6%显示出中等水平的FCR。对复发的恐惧随着时间的推移而减少(p
Background. Fear of cancer recurrence (FCR) or cancer progression is one of the most frequent distressing psychological symptoms in cancer patients. In contrast to anxiety disorders according to the ICD-10 or DSM-IV, FCR describes an emotional response to the real threat of a life-threatening illness. Elevated levels of FCR can become dysfunctional, causing considerable disruption in social functioning, and affect well-being and quality of life (QoL). We examined the prevalence and course of FCR in cancer patients during and after a rehabilitation program, and investigated associations between demographic, medical and psychosocial factors. We further aimed to identify predictors of FCR one year after cancer rehabilitation. Methods. A total of eligible N = 1281 patients (77.5% participation rate) were consecutively recruited on average 11 months post-diagnosis and assessed at the beginning (t(1)) (1148), at the end (t(2)) (1060) and 12 months after rehabilitation (t(3)) (n = 883). Participants completed validated measures assessing FCR, anxiety, depression, QoL, social support, and a range of cancer- and treatment-related characteristics. Results. At t(1) 18.1% of our sample was classified as having high levels of FCR and 66.6% showed moderate levels of FCR. Fear of recurrence decreased over time (p