Standing waves and traveling waves distinguish two circuits in visual cortex
Standing waves and traveling waves distinguish two circuits in visual cortex
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DOI：
10.1016/j.neuron.2007.06.017
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发表时间：
2007-07-05
期刊：
影响因子：
16.2
通讯作者：
Carandini, Matteo
中科院分区：
文献类型：
--
作者：
Benucci, Andrea;Frazor, Robert A.;Carandini, Matteo
视觉皮质通过神经元群体的活动来代表刺激。我们通过成像CAT区域V1中的电压敏感染料来测量这种活性在空间和时间上的演变。对比度反转刺激引起的反应以两倍于刺激频率的频率振荡，表明信号主要起源于复杂的细胞。这些反应不受噪声的干扰，噪声的幅度以1/频率的幅度下降，并产生高分辨率的定向偏好和视网膜复制地图。我们首先展示这些地图是如何组合在一起的，以产生对焦点定向刺激的反应。然后，我们研究了振荡活动在空间和时间上的演化。在方向域中，它是一个驻波。在空间域，它是以0.2-0.5m/S的速度传播的行波。这些不同的动力学表明，位置和方向选择性这两个关键刺激属性的基础电路存在根本区别。
The visual cortex represents stimuli through the activity of neuronal populations. We measured the evolution of this activity in space and time by imaging voltage-sensitive dyes in cat area V1. Contrast-reversing stimuli elicit responses that oscillate at twice the stimulus frequency, indicating that signals originate mostly in complex cells. These responses stand clear of the noise, whose amplitude decreases as 1/frequency, and yield high-resolution maps of orientation preference and retinotopy. We first show how these maps are combined to yield the responses to focal, oriented stimuli. We then study the evolution of the oscillating activity in space and time. In the orientation domain, it is a standing wave. In the spatial domain, it is a traveling wave propagating at 0.2-0.5 m/s. These different dynamics indicate a fundamental distinction in the circuits underlying selectivity for position and orientation, two key stimulus attributes.