Relative Peripheral Hyperopia Does Not Predict Development and Progression of Myopia in Children
Relative Peripheral Hyperopia Does Not Predict Development and Progression of Myopia in Children
复制标题
相对周边远视不能预测儿童近视的发生和进展
DOI：
10.1167/iovs.15-17200
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发表时间：
2015-09-01
影响因子：
4.4
通讯作者：
Wang, Ningli
中科院分区：
文献类型：
--
作者：
Atchison, David A.;Li, Shi-Ming;Wang, Ningli
目的。检验相对周边远视可预测近视发展和进展的假设。方法。对 1700 多名 7 岁以上的中国儿童，在基线、1 岁和 2 岁时，在睫状肌麻痹下以 08、6158 和 6308 视野角测量沿水平视野的屈光度，并对 1000 多名 14 岁以上的儿童在基线和 1 岁时测量沿水平视野的屈光度。中心屈光的一种屈光分类是“非近视、近视”(nM、M)，由 nM 大于 -0.50 屈光度（D；等效球镜）和 M 小于或等于 -0.50 D 组成。第二种分类是“远视、正视、低度近视和中度/高度近视”(H、E、LM、MM)，其中 H 大于或等于 +1.00 D、E、 -0.49 至 +0.99 D、LM、-2.99 至 -0.50 D 和 MM 小于或等于 -3.00 D。根据 2 年内近视的发展和进展进行细分。确定不同组的中心屈光随时间的变化，并比较不同亚组之间相对周边屈光随时间的变化。 结果。中心屈光作为相对周边屈光函数的简单线性回归并不能预测近视进展，因为相对周边屈光变得更加远视：相对周边远视和相对周边近视分别预测组/视野角组合的0％和35％的显着近视进展。发生近视的亚组并不比未发生近视的亚组有更多的初始相对周边远视。结论。相对周边远视不能预测儿童近视的发生或进展。这对旨在通过“治疗”相对周边远视来减缓儿童近视进展的治疗效果提出了质疑。
PURPOSE. To test the hypothesis that relative peripheral hyperopia predicts development and progression of myopia.METHODS. Refraction along the horizontal visual field was measured under cycloplegia at visual field angles of 08, 6158, and 6308 at baseline, 1 and 2 years in over 1700 initially 7-year-old Chinese children, and at baseline and 1 year in over 1000 initially 14-year olds. One refraction classification for central refraction was "nonmyopia, myopia'' (nM, M), consisting of nM greater than -0.50 diopters (D; spherical equivalent) and M less than or equal to -0.50 D. A second classification was "hyperopia, emmetropia, low myopia, and moderate/high myopia'' (H, E, LM, MM) with H greater than or equal to +1.00 D, E, -0.49 to +0.99 D, LM, -2.99 to -0.50 D, and MM less than or equal to -3.00 D. Subclassifications were made on the basis of development and progression of myopia over the 2 years. Changes in central refraction over time were determined for different groups, and relative peripheral refraction over time was compared between different subgroups.RESULTS. Simple linear regression of central refraction as a function of relative peripheral refraction did not predict myopia progression as relative peripheral refraction became more hyperopic: relative peripheral hyperopia and relative peripheral myopia predicted significant myopia progression for 0% and 35% of group/visual field angle combinations, respectively. Subgroups who developed myopia did not have more initial relative peripheral hyperopia than subgroups who did not develop myopia.CONCLUSIONS. Relative peripheral hyperopia does not predict development nor progression of myopia in children. This calls into question the efficacy of treatments that aim to slow progression of myopia in children by "treating'' relative peripheral hyperopia.