Multidentate Polymer Coatings for Compact and Homogeneous Quantum Dots with Efficient Bioconjugation
Multidentate Polymer Coatings for Compact and Homogeneous Quantum Dots with Efficient Bioconjugation
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DOI：
10.1021/jacs.5b12378
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发表时间：
2016-03-16
影响因子：
15
通讯作者：
Smith, Andrew M.
中科院分区：
文献类型：
--
作者：
Ma, Liang;Tu, Chunlai;Smith, Andrew M.
量子点是用于检测和成像蛋白质和核酸的荧光纳米颗粒。与有机染料和荧光蛋白相比，这些纳米晶体具有增强的亮度、光稳定性和波长可调谐性，但它们较大的尺寸限制了它们的应用。最近，多齿聚合物涂层已经产生了具有小流体动力学尺寸的稳定量子点（
Quantum dots are fluorescent nanoparticles used to detect and image proteins and nucleic acids. Compared with organic dyes and fluorescent proteins, these nanocrystals have enhanced brightness, photostability, and wavelength tunability, but their larger size limits their use. Recently, multidentate polymer coatings have yielded stable quantum dots with small hydrodynamic dimensions (