Macrophage Activation by Interferon or Interferon Inducers
Macrophage Activation by Interferon or Interferon Inducers
复制标题
干扰素或干扰素诱导剂激活巨噬细胞
DOI：
--
复制
发表时间：
1980
期刊：
影响因子：
--
通讯作者：
M. Daha
中科院分区：
文献类型：
--
作者：
M. Rabinovitch;S. Hamburg;E. Unanue;M. Daha
至少有三种类型的机制可以单独地或组合地成为所施用的药剂激活巨噬细胞的基础：1）药剂可以直接影响巨噬细胞或巨噬细胞前体; 2）药剂可以触发补体、凝血或纤溶酶原级联以产生效应分子，其继而影响巨噬细胞的功能;和3）所述试剂可以诱导巨噬细胞自身、淋巴细胞、粒细胞或其它细胞释放巨噬细胞活化的细胞衍生因子。
There are at least three types of mechanism which singly or in combination may underlie macrophage activation by an administered agent: 1) the agent may directly affect macrophages or macrophage precursors; 2) the agent may trigger the complement, clotting, or plasminogen cascades to generate effector molecules which in turn affect the function of macrophages; and 3) the agent may induce macrophages themselves, lymphocytes, granulocytes or other cells to release cell-derived factors of macrophage activation.