Characteristics of NDM-1-Producing Escherichia coli Isolates That Belong to the Successful and Virulent Clone ST131
Characteristics of NDM-1-Producing Escherichia coli Isolates That Belong to the Successful and Virulent Clone ST131
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DOI：
10.1128/aac.01763-10
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发表时间：
2011-06-01
影响因子：
4.9
通讯作者：
Pitout, Johann D. D.
中科院分区：
文献类型：
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作者：
Peirano, Gisele;Schreckenberger, Paul C.;Pitout, Johann D. D.
1株产NDM-1碳青霉烯酶的大肠埃希菌分离株为产碳青霉烯酶(NDM-1)的产碳青霉烯酶菌株(ST131)，属于系统发育群B2。该菌株是从一名尿路感染患者身上获得的，他最近在访问印度期间住院返回美国。产生NDM-1的大肠杆菌ST131的毒力因子明显多于之前从加拿大患者身上分离的产生NDM-1的大肠杆菌ST101。NDMβ-内酰胺酶在一种非常成功和毒力很强的大肠杆菌序列类型中的存在令人担忧。
An NDM-1 carbapenemase-producing Escherichia coli isolate of sequence type 131 (ST131) that belonged to phylogenetic group B2 was obtained from a patient with a urinary tract infection who returned to the United States after a recent hospitalization while visiting India. NDM-1-producing E. coli ST131 had significantly more virulence factors than NDM-1-producing E. coli ST101, previously isolated from a patient in Canada. The presence of NDM beta-lactamases in a very successful and virulent E. coli sequence type is of concern.