Medical marijuana: more questions than answers.

Medical marijuana: more questions than answers.
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DOI:
10.1097/01.pra.0000454786.97976.96
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发表时间:
2014-09
影响因子:
1.9
通讯作者:
Hill KP
Hill KP
中科院分区:
医学4区
文献类型:
--
作者:
Hill KP

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截至2014年8月,23个州和哥伦比亚特区已经颁布了医用大麻法,重要的是精神科医生能够解决患者,家庭和其他医疗保健专业人员关于医用大麻的问题。作者讨论了合成大麻素和医用大麻的有限医学文献。合成大麻素屈大麻酚和大麻隆被美国食品和药物管理局批准用于患有消耗性疾病如获得性免疫缺陷综合征(AIDS)的患者中与癌症化疗和食欲刺激相关的恶心和呕吐。迄今为止,这些药物用于其他疾病的临床试验结果差异很大。此外,关于将大麻植物用作医疗的数据很少。作者的结论是,显然需要对大麻素的可能医疗用途进行更多的研究。他指出,与潜在的医用大麻患者的讨论应该强调各方之间沟通的重要性,因为大麻治疗可能产生副作用,并且可能与患者可能服用的其他药物相互作用。促进彻底的药物滥用咨询是精神科医生,特别是成瘾精神科医生,随着医用大麻变得越来越普遍,可以产生影响的最积极的方式之一。仔细审查预期医用大麻使用者的物质使用史,共同发生的医疗和精神疾病,家族史和心理社会压力源是至关重要的,在评估这些患者的医用大麻的潜在风险。作者的结论是,精神科医生可以通过增加医用大麻以安全和负责任的方式使用的可能性来产生重大影响。
With 23 states and the District of Columbia having enacted medical marijuana laws as of August 2014, it is important that psychiatrists be able to address questions about medical marijuana from patients, families, and other health care professionals. The author discusses the limited medical literature on synthetic cannabinoids and medical marijuana. The synthetic cannabinoids dronabinol and nabilone are approved by the United States Food and Drug Administration for nausea and vomiting associated with cancer chemotherapy and appetite stimulation in patients with wasting diseases such as acquired immunodeficiency syndrome (AIDS). Results of clinical trials of these agents for other conditions have varied widely thus far. In addition, few data are available on the use of the marijuana plant as a medical treatment. The author concludes that there is a clear need for additional research on possible medical uses of cannabinoids. He notes that discussions with prospective medical marijuana patients should emphasize the importance of communication among all parties due to the possible side effects of treatment with marijuana and its potential to interact with other medications the patient may be taking. Facilitating a thorough substance abuse consultation is one of most positive ways that psychiatrists, especially addiction psychiatrists, can make an impact as medical marijuana becomes increasingly common. A careful review of the prospective medical marijuana user's substance use history, co-occurring medical and psychiatric conditions, family history, and psychosocial stressors is essential in evaluating the potential risks of medical marijuana for these patients. The author concludes that psychiatrists can have a significant impact by increasing the likelihood that medical marijuana will be used in a safe and responsible way.
DOI: 10.1038/mp.2013.61
发表时间: 2013-09
影响因子: 11
作者:
Neumeister, A.;Normandin, M. D.;Pietrzak, R. H.;Piomelli, D.;Zheng, M. Q.;Gujarro-Anton, A.;Potenza, M. N.;Bailey, C. R.;Lin, S. F.;Najafzadeh, S.;Ropchan, J.;Henry, S.;Corsi-Travali, S.;Carson, R. E.;Huang, Y.
通讯作者: Huang, Y.
DOI: 10.1016/j.drugalcdep.2010.11.004
发表时间: 2011-05-01
影响因子: 4.2
作者:
Lopez-Quintero, Catalina;Perez de los Cobos, Jose;Hasin, Deborah S.;Okuda, Mayumi;Wang, Shuai;Grant, Bridget F.;Blanco, Carlos
通讯作者: Blanco, Carlos