Location and dynamics of anthracyclines bound to unilamellar phosphatidylcholine vesicles.
Location and dynamics of anthracyclines bound to unilamellar phosphatidylcholine vesicles.
复制标题
蒽环类药物与单层磷脂酰胆碱囊泡结合的位置和动力学。
DOI：
10.1021/bi00342a043
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发表时间：
1985
期刊：
影响因子：
2.9
通讯作者：
Tritton,TR
中科院分区：
文献类型：
--
作者：
Burke,TG;Tritton,TR
Materials and MethodsChemicals. The sources and drug stock preparation of the anthracycline derivatives have been previously described (Burke & Tritton, 1985). 1, 4-Dihydroxyanthraquinone (Aldrich) was further purified by recrystallization in acetone. La-Dimyristoylphosphatidylcholine, La-dipalmitoyl-phosphatidylcholine, and glycogen were obtained from Sigma1 Abbreviations: DMPC, La-dimyristoylphosphatidylcholine; DPPC, La-dipalmitoylphosphatidylcholine; TLC, thin-layer chromatography; PBS, phosphate-buffered saline containing 8 mM Na2HP04, 1 mM KH2P04, and the specified amount of KC1 or KI (pH 7.4); TM, gel-to liquid-crystalline-phase transition temperature; DPH, 1, 6-diphenyl-1, 3, 5-hexatriene.
