CHELATION AND NONCHELATION CONTROLLED STEREOSELECTIVE REDUCTION OF ALPHA-METHOXY-ALPHA-PHENYLTHIO KETONES
CHELATION AND NONCHELATION CONTROLLED STEREOSELECTIVE REDUCTION OF ALPHA-METHOXY-ALPHA-PHENYLTHIO KETONES
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DOI：
10.1016/s0040-4020(01)80909-1
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发表时间：
1991-06-03
期刊：
影响因子：
2.1
通讯作者：
FUCHICELLO, A
中科院分区：
文献类型：
--
作者：
ANNUNZIATA, R;CINQUINI, M;FUCHICELLO, A
合成了一系列在A1位增加立体中心的α-甲氧基-α-苯硫基取代酮，并研究了络合剂和非络合剂的还原反应。确定了“内部匹配”对(导致高度立体选择性的过程)和“不匹配”对，并提出了可能的过渡结构。
A series of a-methoxy-a-phenylthio substituted ketones bearing an additional stereocenter in a1-position was prepared, and the reduction with chelating and non chelating reagents was studied. ''Internal matched'' pairs (leading to highly stereoselective processes) and ''mismatched'' pairs were identified, and possible transition structures were suggested.