TRANSFER-RNA - THE EARLY ADAPTER
TRANSFER-RNA - THE EARLY ADAPTER
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DOI：
10.1007/bf01047323
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发表时间：
1981-01-01
影响因子：
--
通讯作者：
WINKLEROSWATITSCH, R
中科院分区：
文献类型：
--
作者：
EIGEN, M;WINKLEROSWATITSCH, R
Evolutionary history of tRNA is studied by comparative sequence analysis of two specified tRNA's at various phylogenetic levels and of tRNA families within four different species. Criteria are developed that allow 1) to distinguish between convergent and divergent evolution, 2) to determine the mechanism of divergence and 3) to estimate the degree of randomization of the variable parts of the sequences. The conclusion of these investigations is that tRNA's represent ancient molecules that existed in the form of a mutant distribution prior to their integration into genomes.
