The MPI Bioinformatics Toolkit for protein sequence analysis.

The MPI Bioinformatics Toolkit for protein sequence analysis.
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DOI:
10.1093/nar/gkl217
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发表时间:
2006-07-01
影响因子:
14.9
通讯作者:
Lupas AN
Lupas AN
中科院分区:
生物学2区
文献类型:
--
作者:
Biegert A;Mayer C;Remmert M;Söding J;Lupas AN

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MPI Bioinformatics Toolkit是一个交互式网络服务,提供对各种公共和内部生物信息学工具的访问。它们被分成不同的部分,支持序列搜索,多重比对,二级和三级结构预测和分类。一些公共工具以定制版本提供,扩展了它们的功能。例如,PSI-BLAST可以针对定期更新的标准数据库、定制的用户数据库或可选择的基因组集运行。另一个工具Quick 2D将各种二级结构、跨膜和疾病预测程序的结果整合到一个视图中。该工具包提供了一个友好和直观的用户界面,并带有在线帮助功能。作为一个关键功能,各种工具相互连接,以便一个工具的结果可以转发到其他工具。人们可以运行PSI-BLAST,解析出选定命中的多重比对,并将结果发送到聚类分析工具。工具包框架和内部开发的工具将根据GNU宽松通用公共许可证(LGPL)打包并免费提供。该工具包可访问。
The MPI Bioinformatics Toolkit is an interactive web service which offers access to a great variety of public and in-house bioinformatics tools. They are grouped into different sections that support sequence searches, multiple alignment, secondary and tertiary structure prediction and classification. Several public tools are offered in customized versions that extend their functionality. For example, PSI-BLAST can be run against regularly updated standard databases, customized user databases or selectable sets of genomes. Another tool, Quick2D, integrates the results of various secondary structure, transmembrane and disorder prediction programs into one view. The Toolkit provides a friendly and intuitive user interface with an online help facility. As a key feature, various tools are interconnected so that the results of one tool can be forwarded to other tools. One could run PSI-BLAST, parse out a multiple alignment of selected hits and send the results to a cluster analysis tool. The Toolkit framework and the tools developed in-house will be packaged and freely available under the GNU Lesser General Public Licence (LGPL). The Toolkit can be accessed at .
DOI: 10.1021/bi00176a037
发表时间: 1994-03-15
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
JONES, DT;TAYLOR, WR;THORTON, JM
通讯作者: THORTON, JM
DOI: 10.1110/ps.9.6.1162
发表时间: 2000-06-01
期刊: PROTEIN SCIENCE
影响因子: 8
作者:
Ouali, M;King, RD
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DOI: 10.1002/prot.340230306
发表时间: 1995-11-01
期刊: PROTEINS-STRUCTURE FUNCTION AND GENETICS
影响因子: --
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SALI, A;POTTERTON, L;KARPLUS, M
通讯作者: KARPLUS, M
DOI: 10.1006/jmbi.1999.3091
发表时间: 1999-09-17
影响因子: 5.6
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DOI: 10.1093/bioinformatics/bti125
发表时间: 2005-04-01
期刊: BIOINFORMATICS
影响因子: 5.8
作者:
Söding, J
通讯作者: Söding, J