Incidence of antibiotic-resistant infection in long-term residents of skilled nursing facilities.

Incidence of antibiotic-resistant infection in long-term residents of skilled nursing facilities.
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DOI:
10.1016/j.ajic.2007.10.016
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发表时间:
2008-09
影响因子:
4.9
通讯作者:
Saint S
Saint S
中科院分区:
医学3区
文献类型:
--
作者:
Rogers MA;Mody L;Chenoweth C;Kaufman SR;Saint S

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缺乏关于熟练护理设施居民中耐药感染发生率的信息。在加州、佛罗里达、密歇根、纽约和得克萨斯的3,314个专业护理机构的56,182名长期居民中确定了耐药感染的发病率和预测因素。每年的发病率为12.7例/1000长期居民的整体,这是不同的国家(最高发病率,纽约)和类型的入院设施(最高发病率,康复医院)。年轻居民、男性、截瘫、四肢瘫、周围血管疾病或糖尿病患者的发病率更高。透析、导尿、饲管、气管切开术和静脉药物的使用与风险升高相关。截瘫居民(OR=2.86,95%CI:1.67,4.89)和接受透析的个人(OR=2.84,95%CI:1.84,4.37)的调整后优势比最大。不同的入院诊断、器械使用和设施特征,耐药性感染的风险存在显著差异。
Information regarding the incidence of antibiotic-resistant infection in residents of skilled nursing facilities is lacking. Incidence and predictors of antibiotic-resistant infection were determined in 56,182 long-term residents of 3,314 skilled nursing facilities in California, Florida, Michigan, New York, and Texas. The annual incidence was 12.7 cases per 1000 long-term residents overall, which varied by state (highest incidence, New York) and type of admitting facility (highest incidence, rehabilitation hospital). The incidence was greater in younger residents, males, and in those with paraplegia, quadriplegia, peripheral vascular disease, or diabetes mellitus. Dialysis, urinary catheterization, feeding tubes, tracheostomy, and use of intravenous medications were associated with elevated risk. Adjusted odds ratios were greatest for residents with paraplegia (OR=2.86, 95% CI: 1.67, 4.89) and for individuals receiving dialysis (OR=2.84, 95% CI: 1.84, 4.37). There is significant variation in the risk of antibiotic-resistant infection by admitting diagnoses, device use, and facility characteristics.
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