Procedure for the Synthesis of Polysubstituted Carbazoles from 3-Vinyl Indoles
Procedure for the Synthesis of Polysubstituted Carbazoles from 3-Vinyl Indoles
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由 3-乙烯基吲哚合成多取代咔唑的方法
DOI：
10.1021/acs.orglett.6b03257
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发表时间：
2016
期刊：
影响因子：
5.2
通讯作者：
Guo Qi-Xiang
中科院分区：
文献类型：
--
作者：
Huang Yi-Wei;Li Xiao-Yun;Fu Li-Na;Guo Qi-Xiang
报道了一种简单的布朗斯特酸催化的串联反应，包括分子间亲核加成、取代和分子内环化反应。32个2-吲哚基取代的咔唑以良好至优异的产率生成。基于这种串联反应策略，首次合成了聚1，4-咔唑。初步研究表明，聚（1，4-咔唑）具有良好的热稳定性和光学性能。
A simple Brønsted acid catalyzed tandem reaction, including intermolecular nucleophilic addition, substitution and intramolecular cyclization, in a one-pot manner is described. Thirty two 2-indolyl substituted carbazoles are generated in good to excellent yields. Based on this tandem reaction strategy, the poly(1,4-carbazole) is prepared for the first time. Preliminary studies indicate that the poly(1,4-carbazole) has good thermostability and optical properties.