Grb7 expression and cellular migration in chronic lymphocytic leukemia: a comparative study of early and advanced stage disease
Grb7 expression and cellular migration in chronic lymphocytic leukemia: a comparative study of early and advanced stage disease
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DOI：
10.1038/sj.leu.2403512
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发表时间：
2004-12-01
期刊：
影响因子：
11.4
通讯作者：
Shachar, I
中科院分区：
文献类型：
--
作者：
Haran, M;Chebatco, S;Shachar, I
Grb7 是一种参与细胞迁移的非催化细胞内衔接蛋白，在某些侵袭性和转移性实体瘤中过度表达。我们发现从 I 期和 IV 期患者获得的慢性淋巴细胞白血病 (CLL) 细胞之间 Grb7 的表达水平存在高度显着差异（ P
Grb7, a noncatalytic intracellular adaptor protein involved in cell migration, is overexpressed in certain invasive and metastatic solid tumors. We found a highly significant difference in the level of expression of Grb7 between chronic lymphocytic leukemia (CLL) cells obtained from stage I and stage IV patients ( P