Total Synthesis of (-)-Conophylline and (-)-Conophyllidine

Total Synthesis of (-)-Conophylline and (-)-Conophyllidine
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DOI:
10.1002/anie.201100981
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发表时间:
2011-01-01
影响因子:
16.6
通讯作者:
Fukuyama, Tohru
Fukuyama, Tohru
中科院分区:
化学1区
文献类型:
--
作者:
Han-ya, Yuki;Tokuyama, Hidetoshi;Fukuyama, Tohru

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双取:标题化合物的全合成以高度收敛的方式完成。该方法的特点是区域和非对映选择性Polonovski-Potier型反应的两个spidosperma骨架的耦合和形成的二氢呋喃环。Troc= 2,2,2-三氯乙氧羰基。
Double take: The total syntheses of the title compounds were accomplished in a highly convergent manner. The approach features the regio-and diastereoselective Polonovski-Potier-type reaction for the coupling of two aspidosperma skeletons and the formation of the dihydrofuran ring. Troc= 2, 2, 2-trichloroethoxycarbonyl.