Urinary heavy metals and associated medical conditions in the US adult population
Urinary heavy metals and associated medical conditions in the US adult population
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DOI：
10.1080/09603123.2011.605877
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发表时间：
2012-01-01
影响因子：
3.2
通讯作者：
Vieira, Edgar Ramos
中科院分区：
文献类型：
--
作者：
Mendy, Angelico;Gasana, Janvier;Vieira, Edgar Ramos
重金属的健康效应已被广泛研究，但需要进一步评估，以全面描述其毒性。使用2007-2008年全国健康与营养调查的数据，对1，857名成年人进行了多变量logistic回归分析，以检查尿液重金属与各种医疗条件之间的关系。心血管疾病与镉（OR：4.94，95% CI：1.48-16.56）和铅（OR：5.32，95% CI：1.08-26.21）有关。哮喘与钨（OR：1.72，95%CI：1.15-2.59）和铀（OR：1.52，95%CI：1.01-2.28）有关。肝毒性与钼（OR：3.09，95% CI：1.24-7.73）和铀（OR：4.79，95% CI：1.74-13.19）相关。体重过重与铅（OR：0.72，95% CI：0.52-0.98）、视力下降与钴（OR：0.65，95% CI：0.44-0.95）和铯（OR：0.52，95% CI：0.35-0.77）的关系惊人地呈负相关。这项研究支持了以前的一些潜在关系的证据，并为未来的研究提供了见解。
Health effects of heavy metals have been widely investigated, but further evaluation is required to comprehensively delineate their toxicity. Using data from the 2007-2008 National Health and Nutrition Examination Survey, a multivariate logistic regression analysis was performed on 1,857 adults to examine the relationship between urinary heavy metals and various medical conditions. Cardiovascular diseases were correlated to cadmium (OR: 4.94, 95% CI: 1.48-16.56) and lead (OR: 5.32, 95% CI: 1.08-26.21). Asthma was related to tungsten (OR: 1.72, 95% CI: 1.15-2.59) and uranium (OR: 1.52, 95% CI: 1.01-2.28). Hepatotoxicity was associated with molybdenum (OR: 3.09, 95% CI: 1.24-7.73) and uranium (OR: 4.79, 95% CI: 1.74-13.19). Surprising inverse relationships occurred for excessive weight with lead (OR: 0.72, 95% CI: 0.52-0.98), reduced visual acuity with cobalt (OR: 0.65, 95% CI: 0.44-0.95) and cesium (OR: 0.52, 95% CI: 0.35-0.77). This study supports some previous evidence of potential relationships and provides insights for future research.