Serum 25-Hydroxyvitamin D Concentrations and Prevalence Estimates of Hypovitaminosis D in the US Population Based on Assay-Adjusted Data
Serum 25-Hydroxyvitamin D Concentrations and Prevalence Estimates of Hypovitaminosis D in the US Population Based on Assay-Adjusted Data
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DOI：
10.3945/jn.111.151977
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发表时间：
2012-03-01
影响因子：
4.2
通讯作者：
Tangpricha, Vin
中科院分区：
文献类型：
--
作者：
Ganji, Vijay;Zhang, Xu;Tangpricha, Vin
既往NHANES报告中维生素D缺乏症的患病率未解释分析随时间的变化和漂移。因此，NHANES公布的关于美国人口维生素D状况的报告可能被高估或低估。我们使用NHANES，1988-1994（n = 18，641）和NHANES，2001-2006（n = 23，424）的三个周期的测定调整血清25-羟基维生素D [25（OH）D]数据调查了美国维生素D状态的变化。血清25（OH）D几何平均值的变化和各种血清25（OH）D截点的患病率估计值（
Prevalence of hypovitaminosis D from previous NHANES reports did not account for assay changes and drifts over time. Thus, published NHANES reports on vitamin D status for the U.S. population were likely either over- or underestimated. We investigated changes in vitamin D status in the U.S. using assay-adjusted serum 25-hydroxyvitamin D [25(OH)D] data from NHANES, 1988-1994 (n = 18,641) and three cycles of NHANES, 2001-2006 (n = 23,424). Changes in geometric mean serum 25(OH)D and prevalence estimates for various serum 25(OH)D cut points (