The co-occurrence of leukemoid reaction and hypercalcemia in a patient with endometrial cancer: A case report and literature review.
The co-occurrence of leukemoid reaction and hypercalcemia in a patient with endometrial cancer: A case report and literature review.
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DOI：
10.1177/00368504211004028
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发表时间：
2021-04
期刊：
影响因子：
2.1
通讯作者：
Xu, Zhendong
中科院分区：
文献类型：
--
作者：
Tao, Weimin;Yan, Qin;Zhou, Yao;Wang, Yanli;Liu, Zhiqiang;Xu, Zhendong
Paraneoplastic syndromes are rarely seen in gynecological tumors especially in endometrial cancer. Early identification of paraneoplastic syndromes plays a significant role in the treatment and prognosis of cancer. Here, we reported a rare case with endometrial cancer with a 2.7 cm × 2.2 cm × 3.4 cm lesion in the posterior cervix presenting leukemoid reaction and hypercalcemia as paraneoplastic syndromes simultaneously. During the progress of the endometrial cancer, her leukocyte level rose up to 60.7 × 109/L after anti-infection treatment. Meanwhile, the patient represented a series of severe clinical situation including hypercalcemia, hypokalemia, metabolic alkalosis. and respiratory failure. Finally, the patient died of respiratory circulatory failure 2 weeks later. In addition to symptomatic treatment, possible treatment targeted on the primary tumor as early as possible might help to improve the clinical prognosis.
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