Incidental colonic fluorodeoxyglucose uptake: Correlation with colonoscopic and histopathologic findings
Incidental colonic fluorodeoxyglucose uptake: Correlation with colonoscopic and histopathologic findings
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DOI：
10.1148/radiol.2243011214
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发表时间：
2002-09-01
期刊：
影响因子：
19.7
通讯作者：
Conti, PS
中科院分区：
文献类型：
--
作者：
Tatlidil, R;Jadvar, H;Conti, PS
目得：评估非结直肠癌患者因其他目的而接受全身FDG正电子发射断层扫描（PET）时结肠偶然摄取FDG的模式和程度，并将其与结肠镜和/或组织病理学结果进行比较。27例无已知结直肠癌病史的患者被转诊进行全结肠直肠癌评估，回顾性分析了体部FDG PET和结肠偶发摄取。10例患者进行结肠镜检查，2例进行组织病理学分析，15例同时进行组织病理学分析。结肠FDG摄取模式为结节性局灶性、结节性多灶性、节段性和弥漫性。FDG摄取水平采用与肝脏摄取相关的四分量表进行评分。二项分布被用来计算在组织学检查中发现异常的概率的95%CI，在FDG PET.RESULTS的结果预测：在8例弥漫性摄取模式的结肠镜检查结果是正常的。13例结节性FDG高摄取患者有病理学表现。27例患者中有6例（22%）未被怀疑患有恶性肿瘤，7例患有良性肿瘤。在95%CI下，结节性高FDG摄取意味着至少79%的组织病理学结果可能异常。结肠炎。结论：结肠镜检查是一个合理的下一步进一步诊断检查的患者显示结节性高FDG摄取在结肠的患者。弥漫性FDG摄取通常与结肠镜检查的正常结果相关，而节段性高摄取可能意味着炎症。(C)RSNA，2002年。
PURPOSE: To evaluate the pattern and degree of incidental colonic fluorodeoxyglucose (FDG) uptake in patients without colorectal carcinoma who underwent whole-body FDG positron emission tomography (PET) for other purposes and compare them with colonoscopic and/or histopathologic findings.MATERIALS AND METHODS: Cases of 27 patients without known history of colorectal carcinoma who were referred for evaluation with whole-body FDG PET and displayed incidental colonic uptake were reviewed retrospectively. Colonoscopy was performed in 10 patients; histopathologic analysis, in two; and both, in 15. The colonic FDG uptake patterns were nodular-focal, nodular-multifocal, segmental, and diffuse. The FDG uptake level was scored with a four-point scale in relation to hepatic uptake. Binomial distribution was used to calculate 95% CIs for the probability of finding an abnormality at histologic examination, as predicted by findings at FDG PET.RESULTS: Colonoscopic findings in eight patients with a diffuse uptake pattern were normal. Thirteen patients with nodular high FDG uptake had pathologic findings. Six (22%) of the 27 patients were not suspected of having a malignancy, and seven had benign neoplasms. With a 95% CI, nodular high FDG uptake implies at least a 79% chance that histopathologic findings may be abnormal. Colitis. was seen in five of six patients with a segmental pattern of high FDG uptake.CONCLUSION: Colonoscopy is a reasonable next step for further diagnostic examination of patients who display nodular high FDG uptake in the colon. Diffuse FDG uptake often is associated with normal findings at colonoscopy, while segmental high uptake may imply inflammation. (C) RSNA, 2002.