Isotropic 3D Cartesian single breath-hold CINE MRI with multi-bin patch-based low-rank reconstruction
Isotropic 3D Cartesian single breath-hold CINE MRI with multi-bin patch-based low-rank reconstruction
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DOI：
10.1002/mrm.28267
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发表时间：
2020-04-06
影响因子：
3.3
通讯作者：
Prieto, Claudia
中科院分区：
文献类型：
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作者：
Kustner, Thomas;Bustin, Aurelien;Prieto, Claudia
目的建立一种新的三维心脏CINE图像采集和重建框架，实现单次屏气条件下对左心室和全心脏的各向同性三维心脏CINE图像的采集和重建。方法提出了一种变密度笛卡尔采集方法，该方法具有螺旋轮廓排序、向外向内采样和螺旋臂之间的采集自适应交替微小黄金角/黄金角增量，以在心脏相位内和相位之间提供不相干和非冗余采样。提出了一种新的基于多箱块的低秩重建，称为MB-PROST，利用冗余信息的局部（在一个补丁），非局部（空间邻域内的类似补丁），和时间（在所有心脏相位）的规模与补丁之间的隐式运动对齐。将所提出的基于多箱块的低秩重建重建与压缩感知重建进行比较，而将从所提出的3D CINE框架导出的LV功能参数与从10名健康受试者和15名患者的传统多层2D CINE成像估计的LV功能参数进行比较。结果所提出的框架提供了高空间（1.9 mm（3））和时间分辨率（类似于50 ms）的3D心脏CINE图像，在一个单一的屏气类似于20 s的LV和类似于26 s的健康受试者的整个心脏覆盖。对于LV覆盖范围，患者中具有轻微各向异性分辨率（1.9 x 1.9 x 2.5 mm）的患者，类似于13至15 s的较短屏气持续时间是可行的。3D CINE与2D CINE的左室功能参数一致性较好，偏倚分别为-0.1 mL/0.1 mL，-0.9 mL/-1.0 mL，-0.1%/-0.8%;收缩末期容积、舒张末期容积和射血分数的置信区间分别为+/- 1.7 mL/+/- 3.7 mL、+/- 1.2 mL/+/- 2.6 mL和+/- 1.2%/+/- 3.6%（10例健康受试者/15例患者）。结论该框架能够在单次屏气扫描中实现3D各向同性心脏CINE，扫描时间约为20 s/26 s，可覆盖LV/全心，在LV功能评估方面与临床2D CINE扫描具有良好的一致性。
Purpose To develop a novel acquisition and reconstruction framework for isotropic 3D Cartesian cardiac CINE within a single breath-hold for left ventricle (LV) and whole-heart coverage. Methods A variable-density Cartesian acquisition with spiral profile ordering, out-inward sampling, and acquisition-adaptive alternating tiny golden/golden angle increment between spiral arms is proposed to provide incoherent and nonredundant sampling within and among cardiac phases. A novel multi-bin patch-based low-rank reconstruction, named MB-PROST, is proposed to exploit redundant information on a local (within a patch), nonlocal (similar patches within a spatial neighborhood), and temporal (among all cardiac phases) scale with an implicit motion alignment among patches. The proposed multi-bin patch-based low-rank reconstruction reconstruction is compared against compressed sensing reconstruction, whereas LV function parameters derived from the proposed 3D CINE framework are compared against those estimated from conventional multislice 2D CINE imaging in 10 healthy subjects and 15 patients. Results The proposed framework provides 3D cardiac CINE images with high spatial (1.9 mm(3)) and temporal resolution (similar to 50 ms) in a single breath-hold of similar to 20 s for LV and similar to 26 s for whole-heart coverage in healthy subjects. Shorter breath-hold durations of similar to 13 to 15 s are feasible for LV coverage with slightly anisotropic resolution (1.9 x 1.9 x 2.5 mm) in patients. LV function parameters derived from 3D CINE were in good agreement with 2D CINE, with a bias of -0.1 mL/0.1 mL, -0.9 mL/-1.0 mL, -0.1%/-0.8%; and confidence intervals of +/- 1.7 mL/+/- 3.7 mL, +/- 1.2 mL/+/- 2.6 mL, and +/- 1.2%/+/- 3.6% (10 healthy subjects/15 patients) for end-systolic volume, end-diastolic volume, and ejection fraction, respectively. Conclusion The proposed framework enables 3D isotropic cardiac CINE in a single breath-hold scan of similar to 20 s/similar to 26 s for LV/whole-heart coverage, showing good agreement with clinical 2D CINE scans in terms of LV functional assessment.