A comparative analysis of 375 patients with lateral and medial medullary infarction.
A comparative analysis of 375 patients with lateral and medial medullary infarction.
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对375例外侧和内侧髓质梗塞患者进行了比较分析。
DOI：
10.1002/brb3.2224
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发表时间：
2021-08
影响因子：
3.1
通讯作者：
Hu BL
中科院分区：
文献类型：
--
作者：
Tao LS;Lin JJ;Zou M;Chen SF;Weng YY;Chen KY;Hu BL
很少有研究比较单纯延髓外侧梗死(LMI)和单纯延髓内侧梗死(MMI)的病因和临床特征。所有患者均于2015年1月至2020年7月在温州医科大学第一附属医院和第二附属医院住院。对其危险因素、临床表现、卒中机制及近期预后进行回顾性分析。在纳入的387名患者中，266名(68.7%)患有LMI，109名(28.2%)患有MMI，12名(3.1%)(9名男性和3名女性)LMI合并MMI。我们对375例LMI和MMI患者进行了分析。LMI和MMI的平均年龄分别为59.4岁和62.69岁。采用单因素分析和多因素Logistic回归分析MMI与LMI相关的危险因素。与LMI相比，既往脑梗塞、血糖控制不良和动脉粥样硬化更常与MMI相关。LMI与MMI的临床表现有显著差异。以改良Rankin评分(MRS)作为近期预后评估标准，MMI较LMI差。本研究发现：(1)MMI患者年龄大于LMI患者；(2)既往脑梗死史、血糖控制不良、动脉粥样硬化是MMI的独立危险因素；(3)LMI和MMI的临床表现异质性；(4)MMI患者的近期预后较LMI差。比较延髓内侧梗死和延髓外侧梗死的患者数量最多的是梗塞前、血糖控制差和动脉粥样硬化与MMI比LMI相关的更多的短期预后。
Few studies have compared the etiology and clinical features between pure lateral medullary infarction (LMI) and pure medial medullary infarction (MMI). All patients included were hospitalized at The First Affiliated Hospital and The Second Affiliated Hospital of Wenzhou Medical University from January 2015 to July 2020. Their risk factors, clinical manifestation, stroke mechanisms and short‐term prognosis were analyzed retrospectively. Among the 387 patients enrolled, 266 (68.7%) had LMI, 109 (28.2%) had MMI, and 12 (3.1%) (nine men and three women) had LMI plus MMI. We analyzed the 375 patients of LMI and MMI. The average ages of LMI and MMI were 59.4 years and 62.69 years, respectively. Univariate analysis and multivariable logistic regression was used to investigate the existing risk factors of MMI relative to LMI. Prior infarction, poor glycemic control, and atherosclerosis were more frequently associated with MMI than with LMI. The clinical manifestation was significantly different between LMI and MMI. We used modified Rankin Scale (mRS) score as the short‐term prognostic evaluation criteria, and MMI appeared worse than LMI. This study reveals that: (1) patients with MMI are older than those with LMI; (2) prior infarction, poor glycemic control, and atherosclerosis are independent risk factors of MMI than that of LMI; (3) the clinical manifestations of LMI and MMI are heterogeneous; (4) short‐term prognosis of MMI is worse than LMI. The largest number of patients comparing medial medullary infarction and lateral medullary infarction Prior infarction, poor glycemic control, and atherosclerosis are more frequently associated with MMI than with LMI Short‐time prognosis is worse in MMI than in LMI
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DOI：
10.3988/jcn.2012.8.2.116
发表时间：
2012-06
期刊：
Journal of clinical neurology (Seoul, Korea)
影响因子：
--
作者：
Kim K;Lee HS;Jung YH;Kim YD;Nam HS;Nam CM;Kim SM;Heo JH
通讯作者：
Heo JH
影响因子：
3.4
作者：
Hong, Yue-hui;Zhou, Li-xin;Peng, Bin
通讯作者：
Peng, Bin
影响因子：
9.9
作者：
Tatu, L;Moulin, T;Duvernoy, H
通讯作者：
Duvernoy, H
影响因子：
9.9
作者：
Bassetti, C;Bogousslavsky, J;Bernasconi, A
通讯作者：
Bernasconi, A
影响因子：
14.5
作者：
Urban, PP;Wicht, S;Hopf, HC
通讯作者：
Hopf, HC