The Impact of COVID-19 Pandemic on Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes: A Single-Centre Study in Central Pennsylvania.
The Impact of COVID-19 Pandemic on Prevalence of Diabetic Ketoacidosis at Diagnosis of Type 1 Diabetes: A Single-Centre Study in Central Pennsylvania.
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DOI：
10.1002/edm2.235
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发表时间：
2021-07
影响因子：
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通讯作者：
Bangalore Krishna K
中科院分区：
文献类型：
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作者：
Bogale KT;Urban V;Schaefer E;Bangalore Krishna K
我们进行了这项研究，以调查COVID-19大流行是否影响DKA的发生率以及先前确定的T1 D儿童的风险因素。我们对2017年1月1日至2020年9月14日期间在三级医疗转诊中心新诊断为T1 D的所有儿科患者（年龄≤ 18岁）进行了回顾性分析的扩展。提取T1 D诊断前30天的人口统计学资料、保险范围和临床文件，以评估诊断时的症状、实验室检查值（血糖、HbA 1c、静脉pH值和碳酸氢盐）以及T1 D诊断后30天内的任何医疗服务。纳入了412例T1 D患者[171例女性：241例男性; 370例COVID前患者：42例COVID后患者]。COVID前和COVID后组入院时DKA诊断的百分比非常相似（47% vs. 48%），严重程度也非常相似（13% vs. 14%轻度DKA; 33% vs. 31%中度或重度DKA）。在宾夕法尼亚州中部的冠状病毒大流行期间，新诊断为T1 D的儿科患者的DKA发生率没有波动。我们进行了这项研究，以调查COVID-19大流行是否影响DKA的发生率以及先前确定的T1 D儿童的风险因素。我们对2017年1月1日至2020年9月14日期间在三级医疗转诊中心新诊断为1型糖尿病的所有儿科患者（年龄≤ 18岁）进行了回顾性分析的扩展。在宾夕法尼亚州中部的冠状病毒大流行期间，新诊断为T1 D的儿科患者的DKA发生率没有波动。
We conducted this study to investigate whether the COVID‐19 pandemic impacted the rate of DKA and previously identified risk factors in children presenting with T1D. We performed an extension of a retrospective analysis of all paediatric patients (age ≤ 18) newly diagnosed with T1D within a tertiary care referral centre between 01/01/2017 and 09/14/2020. Demographics, insurance coverage and clinical documents 30 days before their T1D diagnosis were abstracted to assess for symptoms at diagnosis, laboratory values (blood glucose, HbA1c, venous pH and bicarbonate) and any healthcare encounters within 30 days of their diagnosis of T1D. 412 patients with T1D [171 F:241 M; 370 pre‐COVID era:42 post‐COVID era] were included. The percentages of DKA diagnoses at admission were very similar between the pre‐COVID and post‐COVID groups (47% vs. 48%), as were the severity (13% vs. 14% mild DKA; 33% vs. 31% moderate or severe DKA). There were no fluctuations in the rate of DKA among paediatric patients newly diagnosed with T1D throughout the coronavirus pandemic in central Pennsylvania. We conducted this study to investigate whether the COVID‐19 pandemic impacted the rate of DKA and previously identified risk factors in children presenting with T1D. We performed an extension of a retrospective analysis of all paediatric patients (age ≤ 18) newly diagnosed with type 1 diabetes within a tertiary care referral centre between 01/01/2017 and 09/14/2020. There were no fluctuations in the rate of DKA among paediatric patients newly diagnosed with T1D throughout the coronavirus pandemic in central Pennsylvania.