Capsules with silver nanoparticle enrichment subdomains and their antimicrobial properties.
Capsules with silver nanoparticle enrichment subdomains and their antimicrobial properties.
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DOI：
10.1002/asia.200900675
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发表时间：
2010-08
期刊：
影响因子：
--
通讯作者：
Anhe Wang;Yue Cui;Yang Yang-Yang;Junbai Li
中科院分区：
文献类型：
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作者：
Anhe Wang;Yue Cui;Yang Yang-Yang;Junbai Li
报道了具有可控亚微米尺寸亚畴结构的纳米银多层胶囊的制备和银纳米粒子的原位合成。由于聚丙烯酸（PAA）在牺牲核的溶解过程中从胶囊的壳中释放，剩余的聚（4-乙烯基吡啶）（PVP）形成具有可控尺寸的球的子域，其可以通过PVP/PAA双层的数量来调节。这产生了具有特殊表面形态的胶囊，并且使得能够在胶囊壳上的PVP子域内原位合成Ag纳米颗粒。此外，原位形成的银纳米粒子在pH 2.0的溶液中可以主要从PVP的胶囊子域释放，而它们在中性溶液中是稳定的。这些特殊设计的含有Ag纳米颗粒的胶囊可用作抗菌材料，并可能有利于通过激光活化进行远程药物释放。
The fabrication of polyelectrolyte multilayer capsules with controllable submicron-sized subdomains and the in situ synthesis of silver nanoparticles are reported. Because poly(acrylic acid) (PAA) is released from the shell of the capsules in the dissolution process of sacrificial cores, the remaining poly(4-vinylpyridine) (PVP) forms subdomains of spheres with controllable sizes, which can be tuned by the number of PVP/PAA bilayers. This creates capsules with special surface morphology and enables the in situ synthesis of Ag nanoparticles within the PVP subdomains on the shell of capsules. In addition, the in-situ formed Ag nanoparticles can be mostly released from PVP subdomains of capsules in pH 2.0 solution, whereas they are stable in neutral solution. These specially designed capsules containing Ag nanoparticles can be used as antimicrobial materials and potentially benefit remote drug release by laser activation.