Professionally designed information materials and telephone reminders improved consent response rates: evidence from an RCT nested within a cohort study.
Professionally designed information materials and telephone reminders improved consent response rates: evidence from an RCT nested within a cohort study.
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DOI：
10.1016/j.jclinepi.2015.03.014
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发表时间：
2015-08
影响因子：
7.2
通讯作者：
Macleod J
中科院分区：
文献类型：
--
作者：
Boyd A;Tilling K;Cornish R;Davies A;Humphries K;Macleod J
调查不同的研究与参与者沟通方法是否会增加响应，增加难以参与者的响应，并影响参与者的同意决定。雅芳家长和儿童纵向研究中的一项随机对照试验。队列成员被邀请在18岁时重新入组，并同意与他们的健康和行政记录相关联。参与者随机接受三种干预措施的八种组合之一：事先通知明信片或无联系，标准或专业设计的同意包，以及电话或邮政提醒。主要结局是返回知情同意书（“响应”），同意决定是次要结局。在1,950名参与者中，806人（41%）做出了回应。接受设计包装的患者的回复率比接受标准包装的患者高2.7%（95%置信区间：-0.06，5.5%; P = 0.06），接受电话提醒的患者的回复率比接受邮政提醒的患者高6.4%（2.3，10.6%; P = 0.002）。事先通知明信片不影响应答率[差异= 0%（-2.8，2.8%; P = 1.0）]，我们没有发现沟通方法影响同意决定的证据。本试验提供的证据表明，沟通材料的设计可以影响响应率，电话提醒具有优于设计材料的上级成本/效益回报。对传播战略的实验性评估和研究结果的传播可能有益于队列研究。
To investigate whether different study-to-participant communication methods increase response, increase response from hard-to-engage individuals, and influence participants' consent decisions. A randomized controlled trial within the Avon Longitudinal Study of Parents and Children. Cohort members were invited to re-enroll at age 18 and consent to linkage to their health and administrative records. Participants were randomized to receive one of eight combinations of three interventions: a prior-notification postcard or no contact, a standard or professionally designed consent pack, and a phone or postal reminder. The primary outcome was return of the consent form (“response”), with consent decision being the secondary outcome. Of 1,950 participants, 806 (41%) responded. Response rates were 2.7% higher (95% confidence interval: −0.06, 5.5%; P = 0.06) among those receiving designed packs than among those receiving standard packs and 6.4% higher (2.3, 10.6%; P = 0.002) among those receiving phone reminders (compared with postal reminders). The prior-notification postcard did not influence response rates [difference = 0% (−2.8, 2.8%; P = 1.0)], and we found no evidence that the communication method influenced consent decision. This trial provides evidence that communication material design can influence response rates and that phone reminders have superior cost/benefit returns over designed materials. Experimental evaluation of communications strategies and dissemination of findings may benefit cohort studies.