Analysis of Higher-Order Aberrations in a Large Clinical Population
Analysis of Higher-Order Aberrations in a Large Clinical Population
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DOI：
10.1167/iovs.12-10610
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发表时间：
2012-11-01
影响因子：
4.4
通讯作者：
Atchison, David A.
中科院分区：
文献类型：
--
作者：
Hartwig, Andreas;Atchison, David A.
目的.目的利用一个临床人群的大型波前数据库来研究屈光和高阶像差之间的关系以及左右眼像差之间的关系。从Carl Zeiss Vision的欧洲波前数据库中分析了约24，000名患者的三阶和四阶像差系数和高阶均方根像差（HO RMS），缩放至4.5 mm直径的瞳孔尺寸。相关性进行了测定之间的像差和变量的折射，近除了，和圆柱体。大多数像差系数显着依赖于这些变量，但这些因素可以解释的像差的比例小于2%，除了球面像差（12%），水平彗差（9%），HO RMS（7%）。近加光是水平彗差的主要贡献者（9.5%中的8.5%），球镜当量是球面像差的主要贡献者（11.6%中的7.7%）。两眼间的相关性是非常显着的所有像差系数，在0.16和0.81之间变化。屈光参差是三种像差（垂直彗差、继发性散光和四叶像差）的重要变量，但由于可以通过屈光解释的像差比例很小（所有
PURPOSE. To use a large wave-front database of a clinical population to investigate relationships between refractions and higher-order aberrations and between aberrations of right and left eyes.METHODS. Third-and fourth-order aberration coefficients and higher-order root-mean-squared aberrations (HO RMS), scaled to a pupil size of 4.5-mm diameter, were analyzed in a population of approximately 24,000 patients from Carl Zeiss Vision's European wave-front database. Correlations were determined between the aberrations and the variables of refraction, near addition, and cylinder.RESULTS. Most aberration coefficients were significantly dependent upon these variables, but the proportion of aberrations that could be explained by these factors was less than 2% except for spherical aberration (12%), horizontal coma (9%), and HO RMS (7%). Near addition was the major contributor for horizontal coma (8.5% out of 9.5%) and spherical equivalent was the major contributor for spherical aberration (7.7% out of 11.6%). Interocular correlations were highly significant for all aberration coefficients, varying between 0.16 and 0.81. Anisometropia was a variable of significance for three aberrations (vertical coma, secondary astigmatism, and tetra-foil), but little importance can be placed on this finding because of the small proportion of aberrations that can be explained by refraction (all