Associations between sleep quality and anxiety and depression symptoms in a sample of young adult twins and siblings
Associations between sleep quality and anxiety and depression symptoms in a sample of young adult twins and siblings
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DOI：
10.1016/j.jpsychores.2011.03.011
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发表时间：
2011-10-01
影响因子：
4.7
通讯作者：
Eley, Thalia C.
中科院分区：
文献类型：
--
作者：
Gregory, Alice M.;Buysse, Daniel J.;Eley, Thalia C.
目的：对睡眠障碍与焦虑和抑郁症状之间的联系的病因学知之甚少。本研究的目的是评估遗传和环境对这些关联的影响。方法：对1556名来自双胞胎和兄弟姐妹(61.5%女性)的年轻人进行问卷调查。结果：睡眠障碍与焦虑症状(r=.39)和抑郁症状(r=.50)呈中度相关。在影响睡眠障碍的基因和影响焦虑和抑郁症状的基因之间有很大的重叠(Ra=0.58)和(Ra=0.68)。总体而言，睡眠与焦虑和抑郁症状之间的关联主要是由于基因(分别解释了74%和58%的协方差)，其余的原因是没有共同的环境因素。结论：表型之间的适度表型和遗传相关性支持了睡眠障碍与各种精神障碍的存在有关的观点，但也值得独立考虑和治疗。(C)2011 Elsevier Inc.保留所有权利。
Objectives: Little is known about the aetiology of the links between sleep disturbance and anxiety and depression symptoms. The aim of this study was to estimate genetic and environmental influences on these associations.Methods: Questionnaires were completed by 1556 young adults from twin and sibling pairs (61.5% female).Results: Sleep disturbance was moderately correlated with symptoms of anxiety (r=.39) and depression (r=.50). There was substantial overlap between genes influencing sleep disturbance and those influencing symptoms of anxiety (rA=.58) and depression (rA=.68). Overall, the associations between sleep and symptoms of both anxiety and depression were mainly due to genes (explaining 74% and 58% of the covariances respectively), with the remainder due to nonshared environmental factors.Conclusions: Moderate phenotypic and genetic correlations between the phenotypes support the view that sleep disturbance is related to the presence of various psychiatric difficulties, but also warrants independent consideration and treatment. (C) 2011 Elsevier Inc. All rights reserved.