Diversity of Neural Precursors in the Adult Mammalian Brain

Diversity of Neural Precursors in the Adult Mammalian Brain
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DOI:
10.1101/cshperspect.a018838
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发表时间:
2016-04-01
影响因子:
7.2
通讯作者:
Song, Hongjun
Song, Hongjun
中科院分区:
生物学1区
文献类型:
--
作者:
Bonaguidi, Michael A.;Stadel, Ryan P.;Song, Hongjun

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在技术进步的帮助下,最近的神经前体身份和调节的研究已经揭示了各种细胞类型作为成年哺乳动物大脑中正在进行的细胞发生的贡献者。在这里,我们使用干细胞生物学作为一个框架,突出成人神经前体群体的多样性,并强调其层次结构,组织和可塑性的生理和病理条件下。
Aided by advances in technology, recent studies of neural precursor identity and regulation have revealed various cell types as contributors to ongoing cell genesis in the adult mammalian brain. Here, we use stem-cell biology as a framework to highlight the diversity of adult neural precursor populations and emphasize their hierarchy, organization, and plasticity under physiological and pathological conditions.