Coupled population dynamics of endosymbionts within and between hosts
Coupled population dynamics of endosymbionts within and between hosts
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DOI：
10.1111/j.1600-0706.2008.17110.x
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发表时间：
2009-03-01
期刊：
影响因子：
3.4
通讯作者：
Jaenike, John
中科院分区：
文献类型：
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作者：
Jaenike, John
许多昆虫物种都感染了母体传播的内共生体，最广泛的记录是沃尔巴克氏体。这些感染的传播速度和流行平衡取决于两个参数-母体传播保真度和受感染细胞质谱系的相对适合度。内共生菌的传输保真度和表型效应通常随宿主内共生菌密度的增加而增加。因此，宿主种群中感染流行的动态取决于影响宿主内内共生体密度的过程。从理论上讲，雄性杀死内共生体的感染的平衡流行率对传输保真度和相对适合度的变化比引起细胞质不相容性的内共生体更敏感。在自然种群中，男性杀手表现出更大的时间和空间变化的感染流行比内共生体，导致细胞质不相容。因此，内共生体感染的种群动态，特别是那些导致男性死亡，很可能是由环境和遗传变量，影响这些感染的宿主内密度。
Many insect species are infected with maternally transmitted endosymbionts, the most widely documented being Wolbachia. The rate of spread and equilibrium of prevalence of these infections depend on two parameters - maternal transmission fidelity and relative fitness of infected cytoplasmic lineages. Both transmission fidelity and the phenotypic effect of endosymbionts often increase with endosymbiont density within hosts. Thus, the dynamics of infection prevalence in host populations depends on processes affecting within-host density of endosymbionts. In theory, the equilibrium prevalence of infection by male-killing endosymbionts is much more sensitive to changes in transmission fidelity and relative fitness than is that of endosymbionts that cause cytoplasmic incompatibility. In natural populations, male-killers exhibit much greater temporal and spatial variation in the prevalence of infection than do endosymbionts that cause cytoplasmic incompatibility. Thus, the population dynamics of endosymbiont infections, especially those that cause male-killing, is likely to be governed by environmental and genetic variables that affect within-host density of these infections.