Highly efficient alkylation of epoxides with R3Al/H2O systems based on the double activation of epoxy oxygens
Highly efficient alkylation of epoxides with R3Al/H2O systems based on the double activation of epoxy oxygens
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DOI：
10.1016/s0040-4039(99)01025-4
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发表时间：
1999-07-16
影响因子：
1.8
通讯作者：
Miyashita, M
中科院分区：
文献类型：
--
作者：
Abe, N;Hanawa, H;Miyashita, M
三烷基铝/水体系可实现环氧化物的烷基化反应，其烷基化效果明显优于母体三烷基铝体系。双齿双（二烷基）铝氧烷及其假想的类似物似乎是环氧底物双活化的活性物质。通过几个合成实例与相应的单齿衍生物进行比较，强调了这种双活化能力。双齿（Me2Al）(2)O的双配位配合物形成用THF用H-1和C-13核磁共振谱进行了表征。1999爱思唯尔科学有限公司版权所有。
Alkylation of epoxides can be effected with trialkylaluminum/water system, which is much superior to the parent trialkylalnminum. Bidentate bis(dialkyl)aluminoxanes and their hypothetical analogues seem to be active species for the double activation of epoxy substrates. Such double-activation ability is emphasized using several synthetic examples in comparison with the corresponding monodentate derivatives. The double coordination complex formation of bidentate (Me2Al)(2)O is characterized with THF by H-1 and C-13 NMR spectroscopy. (C) 1999 Elsevier Science Ltd. All rights reserved.