Economic evaluations of hepatitis B immunization: A global review of recent studies (1994-2000)
Economic evaluations of hepatitis B immunization: A global review of recent studies (1994-2000)
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DOI：
10.1002/hec.625
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发表时间：
2001-12-01
期刊：
影响因子：
2.1
通讯作者：
Beutels, P
中科院分区：
文献类型：
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作者：
Beutels, P
对 1994 年至 2000 年间发表的乙型肝炎 (HBV) 疫苗接种的经济评估进行了检索。这些研究的结果根据 HBV 流行程度进行了讨论。这些评估绝大多数是针对工业化国家进行的，其中大部分位于乙型肝炎病毒流行率低至极低的地区。在流行率极低的国家，经济评估得出了相互矛盾的结果，具体取决于他们使用的流行病学模型的类型。在这些国家，将普遍性添加到选择性疫苗接种策略的成本效益取决于选择性策略充分识别的能力。接触并全面接种不同风险人群的疫苗。在低度、中度和高度流行地区，基于经济评估，普遍接种疫苗似乎是合理的。总的来说，这些年来模型的准确性有所提高。但分析的透明度、完整性和可比性仍然可以大大提高。通过注意到这一点，讨论了不同方法对于不同流行地区和疫苗接种策略的适用性。建议制定专门的传染病预防经济评价指南，保证研究的相关性，提高研究之间的可比性。版权所有 (C) 2001 John Wiley Sons, Ltd.
A search was carried out for economic evaluations of hepatitis B (HBV) vaccination, published between 1994 and 2000. The results of these studies are discussed according to the level of HBV endemicity. The great majority of these evaluations were carried out for industrialized countries., for the most part situated in areas of low to very low HBV endemicity.In countries of very low endemicity economic evaluations have yielded contradictory results, depending on the type of epidemiological model they used. The cost-effectiveness of adding universal to selective vaccination strategies in these countries depends on the selective strategies' ability to sufficiently identify. reach and fully vaccinate persons in various risk groups. In areas of low, intermediate and high endemicity, universal vaccination seems justifiable on the basis of economic evaluation. In general, the accuracy of the models has improved over the years. but still the transparency, completeness and comparability of analyses could improve considerably. By noting this, the suitability of different methodologies for different areas of endemicity and vaccination strategies is discussed. It is recommended that specific guidelines for economic evaluation of the prevention of infectious diseases be developed to guarantee the relevance of and to improve the comparability between studies. Copyright (C) 2001 John Wiley Sons, Ltd.