LEXICAL BUT NOT SEMANTIC PRIMING IN ALZHEIMERS-DISEASE
LEXICAL BUT NOT SEMANTIC PRIMING IN ALZHEIMERS-DISEASE
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DOI：
10.1037/0882-7974.6.4.522
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发表时间：
1991-12-01
影响因子：
3.7
通讯作者：
FRIEDMAN, RB
中科院分区：
文献类型：
--
作者：
GLOSSER, G;FRIEDMAN, RB
阿尔茨海默病(AD)患者存在语义加工障碍的假设被用一种新的词汇启动任务--阈值口语阅读来检验。健康的老年对照组对联想相关的词对(在词联想测试中可靠地同时出现的词)和语义相关的词对(属于同一上级类别但不是高频关联的高频样本)显示出显著的启动效应。AD患者表现出对联想相关词的启动效应，但对仅通过共同语义特征相关的词对则没有启动效应。这些结果与阿尔茨海默病患者语义加工受损的假设一致，表明语义记忆中词与概念之间的独立关系网络可能因不同形式的脑损伤而受到不同程度的破坏。
The hypothesis that patients with Alzheimer's disease (AD) have a disturbance in semantic processing was tested using a new lexical-priming task, threshold oral reading. Healthy elderly controls showed significant effects of priming for word pairs that are associatively related (words that reliably co-occur in word association tests) and for word pairs that are semantically related (high-frequency exemplars that belong to the same superordinate category but are not high-frequency associates). AD patients showed effects of priming for associatively related words but not for word pairs that are related only by shared semantic features. These results are consistent with the hypothesis that semantic processing is impaired in AD and suggest that independent networks of relationships among words and among concepts in semantic memory may be differentially disrupted with various forms of brain damage.