Pilot Study of Improved Lesion Characterization in Breast MRI Using a 3D Radial Balanced SSFP Technique With Isotropic Resolution and Efficient Fat-Water Separation
Pilot Study of Improved Lesion Characterization in Breast MRI Using a 3D Radial Balanced SSFP Technique With Isotropic Resolution and Efficient Fat-Water Separation
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DOI：
10.1002/jmri.21807
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发表时间：
2009-07-01
影响因子：
4.4
通讯作者：
Block, Walter F.
中科院分区：
文献类型：
--
作者：
Moran, Catherine J.;Kelcz, Frederick;Block, Walter F.
目的：评价三维径向平衡稳态自由进动(SSFP)技术提供亚毫米各向同性分辨率和固有的脂肪和水图像体积，并与常规T2加权稀有成像相比，用于乳腺磁共振成像(MRI)的病变定性。材料和方法：3D投影SSFP(3DPR-SSFP)结合了双半回波径向k空间轨迹和线性组合脂肪/水分离技术(线性组合SSFP)。对20名患者进行了一项先导性研究，以评估脂肪抑制和3DPR-SSFP对病变形态的描述。对所有患者的3DPR-SSFP图像体积进行脂肪抑制测量，并将病变形态的描述与相应的T2加权快速自旋回波(FSE)数据集进行比较。结果：与FSE相比，3DPR-SSFP序列的各向同性0.63 mm分辨率显示出更好的病变形态描述。在所有20名患者中，3DPR-SSFP脂肪和水分数据集在5分钟扫描时间内即可获得，而3DPR-SSFP的平均脂肪抑制率为71%。结论：3DPR-SSFP具有改善乳腺MRI可用病变特征信息的潜力，特别是与传统的FSE相比。有必要进行更大规模的研究，以量化3DPR-SSFP对特异性的影响。
Purpose: To assess a 3D radial balanced steady-state free precession (SSFP) technique that provides submillimeter isotropic resolution and inherently registered fat and water image volumes in comparison to conventional T2-weighted RARE imaging for lesion characterization in breast magnetic resonance imaging (MRI).Materials and Methods: 3D projection SSFP (3DPR-SSFP) combines a dual half-echo radial k-space trajectory with a linear combination fat/water separation technique (linear combination SSFP). A pilot study was performed in 20 patients to assess fat suppression and depiction of lesion morphology using 3DPR-SSFP. For all patients fat suppression was measured for the 3DPR-SSFP image volumes and depiction of lesion morphology was compared against corresponding T2-weighted, fast spin echo (FSE) datasets for 15 lesions in 11 patients.Results: The isotropic 0.63 mm resolution of the 3DPR-SSFP sequence demonstrated improved depiction of lesion morphology in comparison to FSE. The 3DPR-SSFP fat and water datasets were available in a 5-minute scan time while average fat suppression with 3DPR-SSFP was 71% across all 20 patients.Conclusion: 3DPR-SSFP has the potential to improve the lesion characterization information available in breast MRI, particularly in comparison to conventional FSE. A larger study is warranted to quantify the effect of 3DPR-SSFP on specificity.