An online randomized controlled trial evaluating HIV prevention digital media interventions for men who have sex with men.
An online randomized controlled trial evaluating HIV prevention digital media interventions for men who have sex with men.
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DOI：
10.1371/journal.pone.0046252
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Margolis AD
中科院分区：
文献类型：
--
作者：
Hirshfield S;Chiasson MA;Joseph H;Scheinmann R;Johnson WD;Remien RH;Shaw FS;Emmons R;Yu G;Margolis AD
由于艾滋病毒感染继续有增无减，有必要针对有风险的男男性行为者采取有效的干预措施。让男男性接触者在网上与性伴侣接触，对艾滋病毒预防工作至关重要。一项随机对照试验（RCT）在从几个同性恋性网络网站招募的美国MSM中在线进行，评估了2个HIV预防视频和一个HIV预防网页与对照条件相比对研究结果HIV检测，血清状态披露和无保护肛交（UAI）的影响。由于保留率低（53%，n = 1，631）导致功率降低，因此合并了视频条件。 没有提供参与者奖励。3,092名合格男性中有1,631名（53%）完成了随访。在干预后的60天内，合并视频条件下的男性比对照组的男性更有可能报告与其最后一个性伴侣的完整血清状态披露（“询问和告知”）（OR 1.32，95% CI 1.01-1.74）。比较基线与随访，合并视频（OR 0.70，95%CI 0.54-0.91）和网页条件（OR 0.43，95%CI 0.25-0.72）中的HIV阴性男性在随访时显著降低了UAI。在随访时，合并视频条件下的HIV阳性男性显著降低了UAI（OR 0.38，95% CI 0.20-0.67）和血清不一致UAI（OR 0.53，95% CI 0.28-0.96）。这项从性网络网站招募的MSM在线RCT的结果表明，旨在进行批判性思维的低成本，简短的数字媒体干预可以增加对性伴侣的艾滋病毒披露并降低性风险。以数字媒体为特色的有效、简短的艾滋病毒预防干预措施可以作为整体行为和生物医学战略的补充部分，通过解决目标人群的具体需求和情况，并通过改变个人知识、动机和社区规范来降低性风险。ClinicalTrials.gov NCT00649701
As HIV infection continues unabated, there is a need for effective interventions targeting at-risk men who have sex with men (MSM). Engaging MSM online where they meet sexual partners is critical for HIV prevention efforts. A randomized controlled trial (RCT) conducted online among U.S. MSM recruited from several gay sexual networking websites assessed the impact of 2 HIV prevention videos and an HIV prevention webpage compared to a control condition for the study outcomes HIV testing, serostatus disclosure, and unprotected anal intercourse (UAI) at 60-day follow-up. Video conditions were pooled due to reduced power from low retention (53%, n = 1,631). No participant incentives were provided. Follow-up was completed by 1,631 (53%) of 3,092 eligible men. In the 60 days after the intervention, men in the pooled video condition were significantly more likely than men in the control to report full serostatus disclosure (‘asked and told’) with their last sexual partner (OR 1.32, 95% CI 1.01–1.74). Comparing baseline to follow-up, HIV-negative men in the pooled video (OR 0.70, 95% CI 0.54–0.91) and webpage condition (OR 0.43, 95% CI 0.25–0.72) significantly reduced UAI at follow-up. HIV-positive men in the pooled video condition significantly reduced UAI (OR 0.38, 95% CI 0.20–0.67) and serodiscordant UAI (OR 0.53, 95% CI 0.28–0.96) at follow-up. Findings from this online RCT of MSM recruited from sexual networking websites suggest that a low cost, brief digital media intervention designed to engage critical thinking can increase HIV disclosure to sexual partners and decrease sexual risk. Effective, brief HIV prevention interventions featuring digital media that are made widely available may serve as a complementary part of an overall behavioral and biomedical strategy for reducing sexual risk by addressing the specific needs and circumstances of the target population, and by changing individual knowledge, motivations, and community norms. ClinicalTrials.gov NCT00649701
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影响因子：
3.7
作者：
Blas MM;Alva IE;Carcamo CP;Cabello R;Goodreau SM;Kimball AM;Kurth AE
通讯作者：
Kurth AE
基于网络的干预措施降低男男性接触者性风险的功效。
影响因子：
4.4
作者：
Carpenter, Kelly M.;Stoner, Susan A.;Mikko, Aneke N.;Dhanak, Lynn P.;Parsons, Jeffrey T.
通讯作者：
Parsons, Jeffrey T.
DOI：
10.1007/s11524-005-9008-3
发表时间：
2006-01-01
影响因子：
6.6
作者：
Chiasson, MA;Parsons, JT;Remien, RH
通讯作者：
Remien, RH
DOI：
10.1080/09540120902730013
发表时间：
2009-01-01
影响因子：
1.7
作者：
Chiasson, Mary Ann;Shaw, Francine Shuchat;Hartel, Diana
通讯作者：
Hartel, Diana
DOI：
10.1097/qai.0b013e3181fcb878
发表时间：
2010-12-15
影响因子：
3.6
作者：
Chiasson, Mary Ann;Hirshfield, Sabina;Rietmeijer, Cornelis
通讯作者：
Rietmeijer, Cornelis