Novel rhodium catalyst for asymmetric hydroformylation of styrene: Study of electronic and steric effects of phosphorus seven-membered ring ligands
Novel rhodium catalyst for asymmetric hydroformylation of styrene: Study of electronic and steric effects of phosphorus seven-membered ring ligands
复制标题
DOI：
10.1016/j.molcata.2007.10.023
复制
发表时间：
2008-02-04
影响因子：
--
通讯作者：
Beller, Matthias
中科院分区：
文献类型：
--
作者：
Erre, Giulia;Enthaler, Stephan;Beller, Matthias
研究了单齿磷杂庚环配体修饰的铑配合物催化苯乙烯的不对称加氢反应。磷取代基的催化活性和选择性的系统变化的影响，以及与几个市售配体的混合配体络合物的形成的组合方法的结果。有效的催化体系已被设计用于该反应，提供在24小时内完全转化和区域选择性高达96%的支链醛和对映选择性高达48%。使用由联萘基支撑的七元磷杂环单元构建的双齿配体不允许进一步改善反应结果。(C)2007 Elsevier B.V.保留所有权利。
The asymmetric hydroformylation of styrene catalysed by rhodium complexes modified by monodentate phosphepine ligands has been investigated. The effects of a systematic variation of the phosphorus substituent on catalytic activity and selectivity are reported as well as the outcome of a combinatorial approach for the formation of mixed ligands complexes with several commercially available ligands. Effective catalytic systems have been devised for the reaction that provide for full conversion within 24h and regioselectivity up to 96% in the branched aldehyde and enantioselectivities up to 48%. The use of bidentate ligands built up by binaphthyl-supported seven-membered phosphacyclic units does not allow for further improvement in the reaction outcome. (C) 2007 Elsevier B.V. All rights reserved.