Clinical trials: the challenge of recruitment and retention of participants
Clinical trials: the challenge of recruitment and retention of participants
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DOI：
10.1111/j.1365-2702.2009.03041.x
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发表时间：
2010-01-01
影响因子：
4.2
通讯作者：
Ali, Parveen A.
中科院分区：
文献类型：
--
作者：
Gul, Raisa B.;Ali, Parveen A.
Aims and Objectives.This article，based on the available literature，tries to discuss the importance of recruitment and retention of research participants，the associated barriers and challenges，and various strategies to overcome these barriers.Background.无法招募和留住所需的参与者在一个研究项目构成严重威胁的内部和外部效度的研究。征聘和留用问题尽管影响严重，但在研究和出版物中没有得到应有的重视。文献表明，缺乏协调的努力来收集临床试验和人群研究中招募经验结局的信息。研究经常提到拒绝参与的参与者数量;然而，大多数的研究往往没有提到的具体原因不足的招募或保留的参与者。设计。一个方法的文件。方法。各种参与者，背景，环境与研究在一项研究中，研究了影响参与者招募和保留现象的相关因素。结果：延迟或无效的招募也有经济和道德上的影响。虽然有许多信息分散在学术期刊上的招聘和保留参与者的研究，很少有作者全面处理这个问题。研究人员必须了解招募和保留研究参与者的重要性，相关的障碍和挑战，以及克服这些barriers.Conclusion的各种策略。适当记录和报告招募和保留研究参与者时所面临的问题不仅有助于理解挑战，而且有助于制定克服这一问题的策略。本文试图综合和回顾现有的关于招聘和保留问题的文献，这需要广泛的理论和概念思维作为研究设计的一部分。与实践的相关性。了解与招聘和保留相关的挑战和问题可以帮助研究人员提前思考克服这些问题的策略，从而节省参与者的时间和精力，研究人员和资助机构。
Aims and objectives.This article, based on the available literature, attempts to discuss the importance of recruitment and retention of research participants, the associated barriers and challenges, and various strategies to overcome these barriers.Background.The inability to recruit and retain the required participants in a research project poses serious threats to both the internal and the external validity of a research study. Despite serious implications, the issues of recruitment and retention do not receive due attention in research and publications. Literature suggests a lack of coordinated efforts to collect information on the outcomes of recruitment experiences in clinical trials and population studies. Studies often mention the number of participants who refuse to participate; however, the majority of the studies often fail to mention the specific reasons insufficient recruitment or retention of the participants.Design.A methodological paper.Method.Various participant-, context-, environment- and research-related factors are examined that affect the phenomenon of recruitment and retention of the participants in a study.Results.Delayed or inefficient recruitment also has financial and ethical implications. Although there are many pieces of information scattered throughout academic journals on recruitment and retention of participants in research, few authors have dealt with the issue holistically. It is imperative for researchers to understand the importance of recruitment and retention of research participants, the associated barriers and challenges, and various strategies to overcome these barriers.Conclusion.Appropriate recording and reporting of the problems faced while recruiting and retaining the participants in research studies can help not only in understating the challenge, but will also help in devising the strategies to overcome this problem. This article was an attempt to synthesise and review the available literature on recruitment and retention issues, which demand extensive theoretical and conceptual thinking as part of the research design.Relevance to practice.An understanding of the challenges and issues related to recruitment and retention can help researchers to think ahead about the strategies to overcome these issues and consequently save the time and energy of the participants, researchers and funding agencies.