Anxiety and Depression among Patients with Thyroid Function Disorders.
Anxiety and Depression among Patients with Thyroid Function Disorders.
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DOI：
10.33314/jnhrc.v18i3.2499
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发表时间：
2020-11-13
影响因子：
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通讯作者：
Sharma, Muna
中科院分区：
文献类型：
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作者：
Gorkhali, Binu;Sharma, Sita;Sharma, Muna
背景：精神合并症在甲状腺疾病患者中很常见，使患者的生活质量和疾病管理变得复杂。我们的目的是探讨甲状腺功能障碍患者焦虑和抑郁的患病率，并确定相关特征。方法：对 129 名年龄 20 岁左右的甲状腺疾病患者进行了一项描述性横断面研究。半结构化问卷、贝克焦虑量表和贝克抑郁量表分别用于社会人口特征、焦虑和抑郁。比较组间差异（卡方）或确定相关性（皮尔逊相关系数）。 结果：患者的平均年龄为 38.09±12.68 岁；大多数是女性（102 名，79.1%）和甲状腺功能低下（90 名，69.8%）。焦虑和抑郁的总体患病率分别为50.4%和42.6%。焦虑在女性中更为普遍（54.9% vs 男性 33.3%，p=0.046）、经济地位较低（73.9% vs 较高经济地位的 35.5%，p=0.019）和甲状腺功能亢进（64.1% vs 甲状腺功能减退症的 44.4%，p=0.040）。抑郁症在女性（47.1% vs 男性 25.9%，p=0.048）、Janajati 族群（婆罗门-Chhetri 族为 54.8% vs 31.1%，p=0.002）、较低经济地位（69.6% vs 较高地位者 35.5%，p=0.016）和甲状腺功能亢进（56.4% vs 36.7%）中更为普遍。甲状腺功能减退症，p=0.037）。与职业、婚姻状况、家庭类型、宗教和病程的相关性不显着。结论：焦虑和抑郁在甲状腺疾病患者中非常普遍，特别是在女性、经济状况较低和功能亢进型甲状腺疾病患者中。甲状腺疾病的治疗应包括焦虑和抑郁的治疗；建议对患病率较高的群体进行常规精神病学筛查。
BACKGROUND: Psychiatric comorbidities are common in thyroid disorder patients and complicate patients' life quality as well as disease management. We aimed to explore prevalence of anxiety and depression and identify associated characteristics among patients with thyroid function disorder.METHODS: A descriptive, cross-sectional study was conducted on 129 thyroid disorder patients aged ?20 years. A semi-structured questionnaire, Beck Anxiety Inventory, and Beck Depression Inventory were used for sociodemographic characteristics, anxiety, and depression respectively. Group differences were compared (Chi square) or correlations were determined (Pearson's correlation coefficient).RESULTS: Patients' mean age was 38.09±12.68 years; most were females (102, 79.1%) and hypothyroid (90, 69.8%). Overall prevalence of anxiety and depression were 50.4% and 42.6% respectively. Anxiety was more prevalent in females (54.9% vs 33.3% in males, p=0.046), low economic status (73.9% vs 35.5% in higher status, p=0.019), and hyperthyroid (64.1% vs 44.4% in hypothyroid, p=0.040). Depression was more prevalent in females (47.1% vs 25.9% in males, p=0.048), Janajati ethnic group (54.8% vs 31.1% in Brahmin-Chhetri, p=0.002), lower economic status (69.6% vs 35.5% in higher status, p=0.016), and hyperthyroid (56.4% vs 36.7% in hypothyroid, p=0.037). Associations with occupation, marital status, family type, religion, and duration of illness were not significant.CONCLUSIONS: Anxiety and depression are highly prevalent among thyroid disorder patients, especially in females, lower economic status, and hyperfunction type thyroid disorder. Management of thyroid disorders should incorporate treatment of anxiety and depression; routine psychiatric screening of the groups with higher prevalence is advisable.