MORPHOLOGICAL-CHANGES IN THE UMBILICAL ARTERIES OF BABIES BORN TO PRE-ECLAMPTIC MOTHERS - AN ULTRASTRUCTURAL-STUDY
MORPHOLOGICAL-CHANGES IN THE UMBILICAL ARTERIES OF BABIES BORN TO PRE-ECLAMPTIC MOTHERS - AN ULTRASTRUCTURAL-STUDY
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DOI：
10.1016/s0143-4004(84)80022-3
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发表时间：
1984-01-01
期刊：
影响因子：
3.8
通讯作者：
SINZINGER, H
中科院分区：
文献类型：
--
作者：
DADAK, C;ULRICH, W;SINZINGER, H
The umbilical arteries of babies from 10 normal pregnancies and from 10 babies born to preeclamptic mothers were studied. Ultrastructurally, there were marked abnormalities of umbilical arterial morphology in the pre-eclamptic group. A loss of intercellular junctions, distension of the endoplasmic reticulum and an increase in cell organelles in the endothelial cells leading to a partial de-endothelialization was noted. Smooth muscle cells showed the morphological features of metabolic activation. These ultrastructural findings can be attributed to fetal hypoxia and to disturbances in cellular lipid metabolism; there may be an abnormal fetal arterial blood flow in maternal pre-eclampsia.
