Aneurysm contents as a source of graft infection.
Aneurysm contents as a source of graft infection.
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动脉瘤内容物是移植物感染的来源。
作者：
R. Williams;F. W. Fisher
在过去的5年半中，从68至151例手术治疗的主动脉瘤中采集了培养物。这些培养物由非血液液体、层状凝块、动脉瘤壁的坏死区域或溃疡性动脉粥样硬化斑块制成。从68个培养物中的7个中收获微生物，包括葡萄球菌、大肠杆菌、假单胞菌和溶血性链球菌。所有患者均使用预防性抗生素;然而，除链球菌外，培养的微生物对所选抗生素不敏感。动脉瘤培养阳性的7例患者中有3例死于与感染无关的原因。在4例培养阳性的存活患者中，移植物感染的证据尚未出现。对细菌存在的了解允许基于生物体敏感性的大规模抗生素治疗。
During the past 5 1/2 years, cultures were taken from 68 to 151 surgically treated aortic aneurysms. These cultures were made from nonblood fluids, laminated clot, necrotic areas of the aneurysm wall, or ulcerated atheromatous plaques. Organisms were harvested from seven of the 68 cultures, including Staphylococcus, Escherichia coli, Pseudomonas, and hemolytic Streptococcus. Prophylactic antibiotics were used in all patients; however, the organisms cultured, excepting Streptococcus, were not sensitive to the chosen antibiotics. Three of the seven patients with a positive aneurysm culture died of causes unrelated to infection. Evidence of graft infection has not developed in four surviving patients with positive cultures. Knowledge of the presence of bacteria permitted massive antibiotic therapy based on organism sensitivity.