Combined PET/CT Imaging in Oncology. Impact on Patient Management.
Combined PET/CT Imaging in Oncology. Impact on Patient Management.
复制标题
DOI：
10.1016/s1095-0397(01)00055-3
复制
发表时间：
2000-11-01
期刊：
影响因子：
--
通讯作者：
Townsend, D W.
中科院分区：
文献类型：
--
作者：
Kluetz, P G.;Meltzer, C C.;Townsend, D W.
目的：在这项工作中，我们描述了五个肿瘤患者的临床管理是唯一受益于一种新的扫描仪，收购正电子发射断层扫描（PET）和X射线计算机断层扫描（CT）在同一imaging session.Procedures：共注册2-[F（18）]-氟-2-脱氧-D-葡萄糖（FDG）-PET和CT图像采集使用组合PET/CT扫描仪。病理和临床随访数据被用来确认PET/CT扫描结果。结果：组合PET/CT扫描仪表现出区分恶性病变正常生理FDG摄取的头部和颈部的横纹肌，以及排泄和肠道活动在腹部和骨盆的能力。此外，该技术积极影响病人的管理，通过本地化的手术和放射治疗计划，以及评估肿瘤responsibility.Conclusion：我们的经验表明，同时收购共同注册的PET和CT图像，使医生能够更准确地区分生理和恶性FDG摄取和更准确地定位病变，提高诊断PET在肿瘤学应用的价值。
Purpose: In this work, we describe five oncology patients whose clinical management were uniquely benefited by a novel scanner that acquires positron emission tomography (PET) and x-ray computed tomography (CT) in the same imaging session.Procedures: Co-registered 2-[F(18)]-fluoro-2-deoxy-D-glucose (FDG)-PET and CT images were acquired using a combined PET/CT scanner. Pathology and clinical follow-up data were used to confirm PET/CT scan results.Results: The combined PET/CT scanner demonstrated the ability to distinguish malignant lesions from normal physiologic FDG uptake in the striated muscles of the head and neck as well as excretory and bowel activity in the abdomen and pelvis. Additionally, the technology positively affected patient management through localization for surgical and radiation therapy planning as well as assessment of tumor response.Conclusion: Our experience indicates that simultaneous acquisition of co-registered PET and CT images enabled physicians to more precisely discriminate between physiologic and malignant FDG uptake and more accurately localize lesions, improving the value of diagnostic PET in oncologic applications.