Cardiovascular components of the defence reaction evoked by excitation of neuronal cell bodies in the midbrain periaqueductal grey of the cat
Cardiovascular components of the defence reaction evoked by excitation of neuronal cell bodies in the midbrain periaqueductal grey of the cat
复制标题
猫中脑导水管周围灰质神经元细胞体兴奋引起的防御反应的心血管成分
DOI：
10.1016/0304-3940(85)90383-0
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发表时间：
1985
影响因子：
2.5
通讯作者：
R. Bandler
中科院分区：
文献类型：
--
作者：
A. McDougall;R. Dampney;R. Bandler
在麻醉和麻痹的猫中，将兴奋性氨基酸dl-同型半胱氨酸（DLH）微量注射（0.40 μl）到中脑导水管周围灰质（PAG）中，诱发了防御反应的心血管模式特征，即骨骼肌血管扩张、心动过速和动脉压升高。相反，注射DLH到中脑被盖未能引起心血管成分的防御反应。由于注射DLH去神经元胞体而非轴突，结果表明中脑PAG而非邻近的被盖含有一群神经元，其兴奋激发这些反应。此外，这些数据表明，这样的神经元可能是本地化优先在尾侧半中脑PAG。
In the anaesthetized and paralyzed cat the cardiovascular pattern characteristic of the defence reaction, i.e. skeletal muscle vasodilatation, tachycardia and increased arterial pressure, was elicited by microinjections (0.40 μl) of the excitatory amino acid,dl-homocysteic acid (DLH), into the midbrain periaqueductal grey (PAG) matter. In contrast, injections of DLH into the midbrain tegmentum failed to elicit the cardiovascular components of the defence reaction. As injections of DLH depolarize cell bodies but not axons, the results indicate that the midbrain PAG, but not the adjacent tegmentum, contains a population of neurones whose excitation elicits these reactions. Further, the data suggested that such neurones may be localized preferentially within the caudal half of the midbrain PAG.