Higher heart rate predicts the risk of developing hypertension in a normotensive screened cohort

Higher heart rate predicts the risk of developing hypertension in a normotensive screened cohort
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DOI:
10.1253/circj.71.1755
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发表时间:
2007-11-01
影响因子:
3.3
通讯作者:
Takishita, Shuichi
Takishita, Shuichi
中科院分区:
医学3区
文献类型:
--
作者:
Inoue, Taku;Iseki, Kunitoshi;Takishita, Shuichi

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背景:较高的心率(HR)与心血管疾病发病率和死亡率相关。高血压是一个重要的心血管危险因素。本研究评估了在血压正常的筛选对象中,较高的HR是否与高血压的发展有关。方法与结果在1997年1天健康评估的正常参与者中,我们研究了2000年也参加该计划的参与者(n=4,331; 2,823名男性(65%),1,508名女性;平均年龄47.9岁)。受试者根据1997年的HR分为4组:四分位1 (HR: 58, n=1,033),四分位2 (59)
Buckground A higher heart rate (HR) is associated with cardiovascular morbidity and mortality. Hypertension is an important cardiovascular risk factor. The present study evaluated whether a higher HR was associated with the development of hypertension in normotensive, screened subjects.Methods and Results Among normotensive participants of a 1-day health evaluation in 1997, we studied those who also participated in the program in 2000 (n=4,331; 2,823 men (65%), 1,508 women; mean age 47 9 years). Subjects were divided into 4 groups based on their HR in 1997: quartile 1 (HR: 58, n=1,033), quartile 2 (59