Responses of extralemniscal thalamic neurones to stimulation of the fastigial nucleus and influences of the cerebellar cortex in the cat
Responses of extralemniscal thalamic neurones to stimulation of the fastigial nucleus and influences of the cerebellar cortex in the cat
复制标题
猫丘脑丘脑外神经元对顶核刺激的反应和小脑皮质的影响
DOI：
10.1016/0006-8993(76)90083-4
复制
发表时间：
1976
期刊：
影响因子：
2.9
通讯作者：
S. Murayama
中科院分区：
文献类型：
--
作者：
K. Kitano;Y. Ishida;Toshio Ishikawa;S. Murayama
图1所示。丘脑层内神经元对同侧(A)和对侧(B)桡浅神经刺激的反应，具有典型的收敛反应模式。C：与(A)和(B)相同的神经元对对侧顶突刺激的反应。D：对耻骨刺激的短潜伏期和长潜伏期反应。E：丘脑神经元的自发单位放电，受到对顶状核的单一电击的抑制。校准：20毫秒A， B和C；D、E各50毫秒；5毫伏振幅。此外，这些反应对重复的周围刺激极其微弱，很少跟随超过8赫兹的刺激率。这些层间神经元反应的电生理特性与其他研究者报道的结果一致[7,10 -12]，这在我们的实验中对识别层间神经元对尖波刺激的反应非常有用。在研究的153个单个单元中，121个（79~ 0）单元对正状核、上颌桡神经和对侧桡神经的所有电刺激都有反应（图1A-C）。6个（4~）只对体表刺激有反应，26个（17~ 0）只对外周刺激有反应。所研究的神经元均在A 6.5 ~ 8.0、L 1.0 ~ 3.0、H+ 3.0 ~—2.0的立体定向范围内，电极迹线的组织学重建显示它们位于正中核和环束旁核。然而，在目前的实验中，以下的研究是对同时对体表和外周刺激作出反应的单元进行的。
Fig. 1. Responses of an intralaminar thalamic neurone to ipsilateral (A) and contralateral (B) superficial radial nerve stimulation with a typical response pattern of convergence. C: response of the same neurone as (A) and (B) to the contralateral fastigial stimulation. D: short and long latency responses to fastigial stimulation. E: spontaneous unit discharge of a thalamic neurone inhibited by a single shock to the fastigial nucleus. Calibrations: 20 msec for A, B and C; 50 msec for D and E; 5 mV amplitude.B). Moreover those responses were extremely weak to repetitive peripheral stimuli and rarely followed stimulation rates in excess of 8 Hz. These electrophysiological properties of intralaminar neuronal responses were in good accordance with results reported by other investigators7, 10-12 and were quite useful in our experiments for the identification of intralaminar neurones responding to fastigial stimulation. Among a total of 153 single units studied, 121 (79~ o) units responded to all electrical stimulation of the fastigial nucleus and of the ipsi-and contralateral radial nerve (Fig. 1A-C). Six (4~) units responded only to fastigial stimulation and 26 (17~ o) units responded only to peripheral stimulation. All the neurones studied were encountered within the stereotaxic limits: A 6.5-8.0, L 1.0-3.0, H+ 3.0 to--2.0, and according to the histological reconstruction by electrode tracks they were located in nucleus centrum medianum and nucleus parafascicularis. In the present experiments, however, the following studies were made on units which responded both to fastigial and peripheral stimulation.