Dogslife: A web-based longitudinal study of Labrador Retriever health in the UK
Dogslife: A web-based longitudinal study of Labrador Retriever health in the UK
复制标题
DOI：
10.1186/1746-6148-9-13
复制
发表时间：
2013-01-18
影响因子：
2.6
通讯作者：
de Bronsvoort, B. Mark C.
中科院分区：
文献类型：
--
作者：
Clements, Dylan N.;Handel, Ian G.;de Bronsvoort, B. Mark C.
背景：Dogslife是第一个大规模的基于互联网的犬类健康纵向研究。这项研究旨在研究环境和遗传因素如何影响英国纯种拉布拉多猎犬的健康和发育。结果：在研究的前12个月，招募了1407只在Kennel Club （KC）注册的合格狗，平均年龄为119日龄（SD 69天，范围3 - 504天）。招募率取决于研究团队与业主联系的能力。在主人授权提供联系方式的情况下，8.4%的狗被招募，而在不可能直接联系的情况下，只有1.3%的狗被招募。如果主人把小狗的登记从饲养员那里转到自己的KC那里，或者主人收到电子邮件或明信片要求参加这个项目，那么被招募的狗的比例会更高。对每月更新的依从性变化很大。在2011年6月30日，对于280只出生400天或以上的狗，我们估计39%到45%的主人仍然积极参与这个项目。初步评估表明，该队列代表了有资格参加该项目的KC注册拉布拉多寻回犬的一般人群。在Dogslife登记的拉布拉多猎犬中，有44.3%报告了疾病的临床症状（首次发病的中位年龄为138天），尽管其中只有44.1%导致了兽医表现（中位年龄为316天）。结论：基于网络的平台使招募具有代表性的KC注册拉布拉多寻回犬成为可能，提供了第一次大规模的犬类健康纵向种群研究。使用多种不同的方法（电子邮件，邮政和电话）与狗主人联系对于最大限度地招募和保留这一群体至关重要。
Background: Dogslife is the first large-scale internet-based longitudinal study of canine health. The study has been designed to examine how environmental and genetic factors influence the health and development of a birth cohort of UK-based pedigree Labrador Retrievers.Results: In the first 12 months of the study 1,407 Kennel Club (KC) registered eligible dogs were recruited, at a mean age of 119 days of age (SD 69 days, range 3 days - 504 days). Recruitment rates varied depending upon the study team's ability to contact owners. Where owners authorised the provision of contact details 8.4% of dogs were recruited compared to 1.3% where no direct contact was possible. The proportion of dogs recruited was higher for owners who transferred the registration of their puppy from the breeder to themselves with the KC, and for owners who were sent an e-mail or postcard requesting participation in the project. Compliance with monthly updates was highly variable. For the 280 dogs that were aged 400 days or more on the 30th June 2011, we estimated between 39% and 45% of owners were still actively involved in the project. Initial evaluation suggests that the cohort is representative of the general population of the KC registered Labrador Retrievers eligible to enrol with the project. Clinical signs of illnesses were reported in 44.3% of Labrador Retrievers registered with Dogslife (median age of first illness 138 days), although only 44.1% of these resulted in a veterinary presentation (median age 316 days).Conclusions: The web-based platform has enabled the recruitment of a representative population of KC registered Labrador Retrievers, providing the first large-scale longitudinal population-based study of dog health. The use of multiple different methods (e-mail, post and telephone) of contact with dog owners was essential to maximise recruitment and retention of the cohort.