Folic acid for the prevention of neural tube defects. American Academy of Pediatrics. Committee on Genetics.
Folic acid for the prevention of neural tube defects. American Academy of Pediatrics. Committee on Genetics.
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美国儿科学会赞同美国公共卫生服务(USPHS)的建议，即所有有能力怀孕的女性每天摄入400微克叶酸，以防止神经管缺陷(NTDS)。研究表明，孕周补充叶酸可以预防50%或更多的NTDS，如脊柱裂和无脑畸形。疾病控制和预防中心(CDC)建议，对于以前有过NTD影响的怀孕女性，从怀孕前至少一个月开始，一直持续到怀孕的前三个月，将叶酸的摄入量增加到每天4000微克。执行这些建议对于初级预防这些严重和致残的出生缺陷至关重要。由于只有不到三分之一的妇女摄入USPHS推荐的叶酸量，该学会指出，预防NTDS有赖于紧急而有效的运动来弥合这一预防差距。
The American Academy of Pediatrics endorses the US Public Health Service (USPHS) recommendation that all women capable of becoming pregnant consume 400 microgram of folic acid daily to prevent neural tube defects (NTDs). Studies have demonstrated that periconceptional folic acid supplementation can prevent 50% or more of NTDs such as spina bifida and anencephaly. For women who have previously had an NTD-affected pregnancy, the Centers for Disease Control and Prevention (CDC) recommends increasing the intake of folic acid to 4000 microgram per day beginning at least 1 month before conception and continuing through the first trimester. Implementation of these recommendations is essential for the primary prevention of these serious and disabling birth defects. Because fewer than 1 in 3 women consume the amount of folic acid recommended by the USPHS, the Academy notes that the prevention of NTDs depends on an urgent and effective campaign to close this prevention gap.