Quantification of rotational thallium-201 myocardial tomography.

Quantification of rotational thallium-201 myocardial tomography.
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DOI:
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发表时间:
1985
期刊:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子:
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通讯作者:
Ernest V. Garcia;K. V. Train;J. Maddahi;F. Prigent;J. Friedman;J. Areeda;A. Waxman;D. Berman
Ernest V. Garcia;K. V. Train;J. Maddahi;F. Prigent;J. Friedman;J. Areeda;A. Waxman;D. Berman
中科院分区:
其他
文献类型:
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作者:
Ernest V. Garcia;K. V. Train;J. Maddahi;F. Prigent;J. Friedman;J. Areeda;A. Waxman;D. Berman

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本文描述了一种全面的方法来定量TL-201在心肌中的相对三维分布,在应激和随后的清洗之后。该方法使用定义明确的长轴和短轴断层图像的最大计数圆周轮廓来确定TL-201的三维分布;然后将该分布映射到二维极地表示上。通过自动将每个患者的轮廓与正常轮廓的相应下限进行计算机比较来识别异常的铊分布或洗脱。异常通过使用范围和严重程度的极图表示为整个心肌的百分比。二进制范围图表示异常程度。初步的异常标准是从25名正常人和28名有记录的冠状动脉疾病患者的断层扫描结果中得出的。25例正常人中23例正常,28例冠心病患者中25例异常。此外,计算机输出正确地定位了56个冠脉循环中的46个病变的存在或不存在。
A comprehensive method is described for quantification of the relative 3-dimensional distribution of Tl-201 in the myocardium, following stress and subsequent washout. The method uses maximal-count circumferential profiles of well-defined long- and short-axis tomograms to determine the 3-dimensional distribution of Tl-201; it then maps this distribution onto a 2-dimensional polar representation. Abnormal thallium distribution or washout is identified by automatic computer comparison of each patient's profile with the corresponding lower limits of normal profiles. Abnormality is expressed as a percentage of the entire myocardium by use of polar maps for extent and severity. The binary extent map expresses the degree of abnormality. Preliminary criteria for abnormality were derived from the tomographic results of 25 normals and 28 patients with documented coronary artery disease. The results were normal in 23 of the 25 normals and were abnormal in 25 of the 28 CAD patients. In addition, the computer output correctly localized the presence or absence of disease in 46 of 56 coronary circulations.