Prevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward
Prevalence of and characteristics associated with in-hospital mortality in a Ugandan neurology ward
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DOI：
10.1186/s12883-020-1627-5
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发表时间：
2020-01-31
期刊：
影响因子：
2.6
通讯作者：
Sico, Jason J.
中科院分区：
文献类型：
--
作者：
Diaz, Monica M.;Hu, Xin;Sico, Jason J.
虽然发展中国家的神经系统疾病负担正在增加，但对撒哈拉以南非洲医院收治的神经系统疾病患者的死亡率知之甚少。我们试图描述乌干达神经内科病房的住院死亡率和患者水平的预测因素。方法前瞻性收集乌干达坎帕拉市穆拉戈医院神经内科收治的335例患者的资料。Kaplan-Meier生存曲线和多变量COX比例风险模型用于评估生存率。结果在我们的样本（n = 307）中，35.8%的患者在入院时未得到诊断。中风（27.3%）、头部外伤（19.6%）和疟疾（16.0%）是最常见的诊断。在指数住院期间死亡的56例（18.5%）患者中，入院和死亡时最常见的诊断是中风。校正回归分析显示，死亡时未确诊患者（HR = 7.01 [2.42-20.35], p < .001）和确诊感染患者(HR = 5.21 [2.16-12.58], p =
Background While the burden of neurologic illness in developing countries is increasing, less is known about mortality among patients admitted to sub-Saharan African hospitals with neurologic disease. We sought to characterize the rate and patient-level predictors of in-hospital mortality in a Ugandan Neurology ward.cc. Methods Data was prospectively collected on 335 patients admitted to the Neurology ward of Mulago Hospital, Kampala, Uganda. Kaplan-Meier survival curves and multivariate COX proportional hazard modeling were used to assess survival. Results Within our sample (n = 307), 35.8% received no diagnosis at time of hospital admission. Stroke (27.3%), head trauma (19.6%), and malaria (16.0%) were the most common diagnoses. Among the 56 (18.5%) patients who died during the index hospitalization, the most common diagnosis at admission and at death was stroke. Adjusted regression analysis showed that patients without a diagnosis at time of death (HR = 7.01 [2.42-20.35], p < .001) and those with diagnoses of infections (HR = 5.21 [2.16-12.58], p =